Health Trials

About this trial

The goal of this observational study is to examine the relationship between metabolic syndrome (MetS) and periodontitis, and to evaluate the role of the Dietary Inflammatory Index (DII) in this association.

The main question it aims to answer is:

Does a pro-inflammatory diet, as measured by the DII, increase the risk or severity of periodontitis in individuals with metabolic syndrome?

Participants will include adults who meet the diagnostic criteria for metabolic syndrome. Their periodontal health will be assessed through standard clinical parameters, and dietary data will be collected using a validated food frequency questionnaire to calculate individual DII scores. The study will observe and analyze these factors to explore potential links between diet-induced inflammation, systemic metabolic health, and periodontal outcomes.

Eligibility criteria

Qualifiers

Being between 18 and 65 years of age

Presence of at least three of the following parameters: (For MetS diagnosis) Waist circumference: ≥ 94 cm for men, ≥ 88 cm for women Blood pressure ≥ 130/85 mmHg or taking antihypertensive medication Fasting blood glucose ≥ 100 mg/dl or diagnosed with Type 2 Diabetes Triglycerides ≥ 1.7 mmol/L HDL < 1.29 mmol/L

Having at least 20 teeth

Not having received periodontal therapy in the last 6 months

Disqualifiers

Patients with an active infectious disease,

Those taking medications that could affect periodontal tissues,

History of endocarditis,

Recent antibiotic use (within 4 months),

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

100 Participants
are grouped into 1 trial group

Locations

1
Department of Periodontology of the Faculty of Dentistry of Recep Tayyip Erdogan University53200, RizeRize Province, Turkey (Türkiye)

Sponsors and collaborators

Recep Tayyip Erdogan University Training and Research Hospital

Lead sponsor

Source ClinicalTrials.gov