[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100620222":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":18,"responsibleParty":36,"collaborators":10,"id":40,"slug":10,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":10,"eligibilityCriteria":45,"healthyVolunteers":41,"sex":46,"minAge":47,"maxAge":48,"enrollmentInfo":49,"targetDuration":52,"studyType":53,"phases":10,"briefSummary":54,"conditions":55,"keywords":58,"overallStatus":62,"whyStopped":10,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":72},{"fullName":5,"class":6},"Recep Tayyip Erdogan University Training and Research Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Patients diagnosed with metabolic syndrome",null,"Metabolic syndrome is diagnosed according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP\u002FATP III) criteria. Diagnosis is made by meeting three of the following five criteria: waist circumference: ≥ 94 cm in men and ≥ 88 cm in women, blood pressure ≥ 130\u002F85 mmHg or use of antihypertensive medication, fasting blood glucose ≥ 100 mg\u002FdL or diagnosed type 2 diabetes, triglycerides ≥ 1.7 mmol\u002FL, and HDL \\\u003C 1.29 mmol\u002FL.",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Oguz KOSE, Professor Dr.","CONTACT","+90 541 348 64 65","oguz.kose@erdogan.edu.tr",[19],{"facility":20,"status":10,"city":21,"state":22,"zip":23,"country":24,"cosmosGeoPoint":25,"geoPoint":30,"contacts":31},"Department of Periodontology of the Faculty of Dentistry of Recep Tayyip Erdogan University","Rize","Rize Province","53200","Turkey (Türkiye)",{"type":26,"coordinates":27},"Point",[28,29],40.52194,41.02083,{"lat":29,"lon":28},[32],{"name":33,"role":15,"phone":34,"phoneExt":10,"email":35},"RTEU Faculty of Dentistry, Department of Periodontology","+90 464 222 00 00","dis@erdogan.edu.tr",{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Dilek KARADOĞAN","Assoc. Prof. Dr.","100620222",false,"NCT07354815","Metabolic Syndrome-Associated Periodontal Inflammatory Surface Area","Determination of the Level of Correlation Between Periodontal Inflammatory Surface Area and Metabolic Syndrome-Associated Periodontal Tissue Destruction","Inclusion Criteria:\n\n* Being between 18 and 65 years of age\n* Presence of at least three of the following parameters: (For MetS diagnosis) Waist circumference: ≥ 94 cm for men, ≥ 88 cm for women Blood pressure ≥ 130\u002F85 mmHg or taking antihypertensive medication Fasting blood glucose ≥ 100 mg\u002Fdl or diagnosed with Type 2 Diabetes Triglycerides ≥ 1.7 mmol\u002FL HDL \\\u003C 1.29 mmol\u002FL\n* Having at least 20 teeth\n* Not having received periodontal therapy in the last 6 months\n* Not having taken antibiotics, steroids, and\u002For nonsteroidal anti-inflammatory drugs in the last 3 weeks\n* Not having any autoimmune disease, osteoporosis, or cancer\n* Not taking immunosuppressive medications, oral contraceptives, Not taking bisphosphonates\n* Not being pregnant\n* Not having an active infectious disease (acute hepatitis, tuberculosis, AIDS)\n* Not taking chronic medications that affect periodontal tissues (cyclosporine A, phenytoin)\n* Not taking antioxidant supplements in the last 6 months\n\nExclusion Criteria:\n\n* Patients with active infectious disease,\n* Those taking medications that may affect periodontal tissues,\n* Those who did not sign the informed consent form.","ALL","18 Years","65 Years",{"count":50,"type":51},100,"ESTIMATED","1 Day","OBSERVATIONAL","This study aims to examine the potential of metabolic syndrome (MetS), a systemic, inflammatory disease, to influence the relationship between periodontal inflammatory surface area (PISA) and diabetes and obesity parameters. The primary question addressed by the study is:\n\nCan PISA be used as a significant parameter in the relationship between periodontal disease and MetS? In this context, the relationship between PISA and periodontal clinical parameters and serum parameters directly related to the diagnosis of MetS will be examined.",[56,57],"Metabolic Syndrome (MetS)","Periodontitis",[59,60,61],"metabolic syndrome","periodontitis","periodontal inflammatory surface area","NOT_YET_RECRUITING","2026-01-12",{"date":65,"type":66},"2026-01-21","ACTUAL",{"date":68,"type":51},"2026-02-23",{"date":70,"type":51},"2026-06-30",{"name":5,"class":6},1]