This study aims to evaluate the effect of subthreshold 577 nm micropulse laser photocoagulation in the treatment of initial and refractory cases of Center-Involved Diabetic Macular Edema.
Age ≥18 years.
Both sexes.
Patients with type 1 or 2 diabetes mellitus (DM), best-corrected visual acuity (BCVA) of 20/400 or better, and center-involved DME [defined as a central macular thickness (CMT) of >250 but <700µm measured by spectral-domain optical coherence tomography].
Patients with any level of non-proliferative diabetic retinopathy or proliferative diabetic retinopathy with adequate panretinal photocoagulation (PRP) and no signs of disease activity determined by fluorescein angiography (FA).
Monocular eyes.
Chronic renal failure or renal transplant because of diabetic nephropathy.
Glycated hemoglobin (HbA1c) of more than 10%.
Vitreomacular traction syndrome.
The General Authority for Teaching Hospitals and Institutes
Lead sponsor