Milk And Growth In Children (MAGIC) Born Very Preterm: A Randomized Trial
ConditionPrematurity
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age6-4
SponsorUniversity of Alabama at Birmingham
About this trial
The goal of this multi-center randomized, parallel group trial is to determine the effect of human milk diets ranging between 180 and 200 mL/kg/day on the body composition outcomes of moderately preterm infants born between 27 and 31 weeks of gestation.
Eligibility criteria
Qualifiers
Gestational age between 27 0/7 and 31 6/7 weeks
Birthweight of 1500 grams or less
Human milk feeding during the first 14 days after birth
Full enteral feeding (120mL/kg/day or more) within the first 14 days after birth
Disqualifiers
Necrotizing enterocolitis stage 2 or greater
Spontaneous intestinal perforation
Major congenital/chromosomal anomalies
Terminal illness requiring limited or withheld support
Trial design
Treatments tested in this trial
- Human milk
Treatment groups
486 Participants
are divided into 2 treatment groupsLocations
4University of Alabama at Birmingham35294, BirminghamAlabama, United States
University of Mississippi Medical Center39216, JacksonMississippi, United States
University of Texas Southwestern Medical Center at Dallas75235, DallasTexas, United States
University of Texas Health Science Center at Houston77030, HoustonTexas, United States
Sponsors and collaborators
University of Alabama at Birmingham
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Collaborator
Source ClinicalTrials.gov