Minimally-Invasive Non-Surgical Therapy of Peri-Implantitis
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorSt. Anne's University Hospital Brno, Czech Republic
About this trial
This multicenter, single-masked randomized controlled clinical trial evaluates the effectiveness of minimally-invasive non-surgical therapy (MINST) compared with standard non-surgical peri-implant therapy (NSPT) in patients diagnosed with peri-implantitis. The study investigates clinical outcomes, radiographic bone levels, patient-reported outcomes, and treatment time over 12 months.
Eligibility criteria
Qualifiers
Age ≥18
Peri-implantitis diagnosis (PPD >6 mm, BOP+, bone loss ≥3 mm)
Accessible implant surface without removing suprastructure
FMPS <30%, FMBS <30-35%
Disqualifiers
Antibiotics in last 3 months
Pregnancy/lactation
Uncontrolled diabetes (HbA1c ≥7)
Long-term SPIC (>2 years)
Trial design
Treatments tested in this trial
- Non-Surgical Peri-implant Therapy (NSPT)
- Minimally-Invasive Non-Surgical Therapy (MINST)
Treatment groups
106 Participants
are divided into 2 treatment groupsLocations
1Syndenta s.r.o., Hlinky 92, 603 00 Brno, Czech Republic60300, Brno Czechia
Sponsors and collaborators
St. Anne's University Hospital Brno, Czech Republic
Lead sponsor
King's College London
Collaborator
Source ClinicalTrials.gov