[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100433183":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":29,"responsibleParty":130,"collaborators":10,"id":132,"slug":10,"hasResults":133,"nctId":134,"briefTitle":135,"officialTitle":136,"acronym":137,"eligibilityCriteria":138,"healthyVolunteers":133,"sex":139,"minAge":10,"maxAge":10,"enrollmentInfo":140,"targetDuration":10,"studyType":143,"phases":10,"briefSummary":144,"conditions":145,"keywords":10,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":147,"lastUpdatePostDateStruct":148,"startDateStruct":151,"completionDateStruct":153,"leadSponsor":155,"locationsCount":156},{"fullName":5,"class":6},"Centre Hospitalier Universitaire de Nice","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Mitochondrial diseases",null,"annalysing with methology of multi-OMICS integration we will determined which RNA-Seq data (from muscle or fibroblasts) are the most informative for the interpretation of VUS identified by WES for patients suspected of mitochondrial myopathy.",[13],"Genetic: diagnosis of mitochondrial myopathy",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"GENETIC","diagnosis of mitochondrial myopathy","• Determination of the presence of specific molecular signatures at the RNA level in muscles and fibroblasts from patients",[9],[21],{"name":22,"affiliation":5,"role":23},"SYLVIE BANNWARTH","PRINCIPAL_INVESTIGATOR",[25],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":28},"CONTACT","0492034702","bannwarth.s@chu-nice.fr",[30,47,60,71,82,90,103,110,121],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"CHU de Nice","RECRUITING","Nice","CHU de NICE","06003","France",{"type":38,"coordinates":39},"Point",[40,41],7.26608,43.70313,{"lat":41,"lon":40},[44,45],{"name":10,"role":26,"phone":27,"phoneExt":10,"email":28},{"name":46,"role":23,"phone":10,"phoneExt":10,"email":10},"Sylvie BANNWARTH, Professor",{"facility":48,"status":49,"city":50,"state":36,"zip":10,"country":36,"cosmosGeoPoint":51,"geoPoint":55,"contacts":56},"C.H.R.U. 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Analysis of RNA-Seq and WES results will performed with a computational approach using an autoencoder-based method",[146],"Mitochondrial Diseases","2025-02-21",{"date":149,"type":150},"2025-02-25","ACTUAL",{"date":152,"type":150},"2022-03-07",{"date":154,"type":142},"2025-09-07",{"name":5,"class":6},9]