About this trial
Patients will be asked to visit the study center 2 times, the first time for clinical assessment and a second time for sample collection. Healthy controls will only be asked to visit the study center for sample collection. A sample of blood and saliva will be collected in order to measure CGRP levels and DNA and hormone testing.
Eligibility criteria
Qualifiers
Migraine patients according to ICHD-3 criteria
Healthy controls paired to patient age and sex, without headache and without first degree family history of headache.
Disqualifiers
Presence of any major medical or neurological illness.
Presence of any salivary gland malfunction.
Abuse or dependence to tobacco, alcohol or any drug in the previous 12 months before the enrollment.
Active migraine preventive treatment.
Trial design
Treatments tested in this trial
- Saliva test
Treatment groups
Locations
1Sponsors and collaborators
Hospital Universitari Vall d'Hebron Research Institute
Lead sponsor