[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100361639":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":23,"locations":34,"responsibleParty":54,"collaborators":10,"id":58,"slug":10,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":65,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":10,"studyType":72,"phases":10,"briefSummary":73,"conditions":74,"keywords":10,"overallStatus":37,"whyStopped":10,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"McGill University Health Centre\u002FResearch Institute of the McGill University Health Centre","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Antibody-negative",null,"Patient has been found negative for at least three T1D antibodies.\n\nThe investigators will proceed with whole exome sequencing",[13],"Other: None AHT",{"label":15,"type":10,"description":16,"interventionNames":17},"Antibody-positive","Patient has been found to be positive for at least one T1D autoantibody.\n\nNo further studies will be performed as part of the main study.",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"None AHT","No further intervention planned for either group as part of the current study.",[9,15],[24,30],{"name":25,"role":26,"phone":27,"phoneExt":28,"email":29},"Constantin Polychronakos, MD","CONTACT","5144124400","22866","constantin.polychronakos@mcgill.ca",{"name":31,"role":26,"phone":27,"phoneExt":32,"email":33},"Angeliki Makri, MD","22623","angeliki.makri@mcgill.ca",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"The Montreal Children's Hospital","RECRUITING","Montreal","Quebec","H4A 3J1","Canada",{"type":43,"coordinates":44},"Point",[45,46],-73.58781,45.50884,{"lat":46,"lon":45},[49,53],{"name":50,"role":26,"phone":51,"phoneExt":32,"email":52},"Natalija Popovic, PhD","514-934-1934","natalija.popovic@muhc.mcgill.ca",{"name":31,"role":26,"phone":51,"phoneExt":32,"email":33},{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Constantin Polychronakos","Senior investigator","100361639",false,"NCT03988764","Monogenic Diabetes Misdiagnosed as Type 1","Accurate Diagnosis of Diabetes for Appropriate Management","ADDAM","Inclusion Criteria:\n\n* Diagnosis of diabetes under the age of 25 as either type 1 or undetermined type.\n\nExclusion Criteria:\n\n* Existing T1D autoantibody testing with a positive result",true,"ALL","1 Day","25 Years",{"count":70,"type":71},5000,"ESTIMATED","OBSERVATIONAL","The study has two aims:\n\n1. To (1a) determine the frequency of monogenic diabetes misdiagnosed as type 1 diabetes (T1D) and (2) to define an algorithm for case selection.\n2. To discover novel genes whose mutations cause monogenic diabetes misdiagnosed as T1D.",[75,76,77,78,79,80,81],"Diabetes Mellitus, Type 1","Monogenic Diabetes","Neonatal Diabetes","Maturity-onset Diabetes in the Young (MODY)","Wolfram Syndrome","Wolcott-Rallison Syndrome","Mitochondrial Diabetes","2024-12-06",{"date":84,"type":85},"2024-12-10","ACTUAL",{"date":87,"type":85},"2019-09-24",{"date":89,"type":71},"2025-12-31",{"name":5,"class":6},1]