[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100612359":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":25,"locations":31,"responsibleParty":42,"collaborators":18,"id":44,"slug":18,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":45,"sex":51,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":18,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":67,"overallStatus":74,"whyStopped":18,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Chung Shan Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Cold Water Rinse","EXPERIMENTAL","Participants will rinse their mouth with cold water at approximately 15-20°C, four times daily for 30-60 seconds throughout six weeks of radiotherapy, followed by a two-week follow-up period.",[13],"Behavioral: Water Rinse at Different Temperatures",{"label":15,"type":16,"description":17,"interventionNames":18},"Room Temperature Water Rinse","NO_INTERVENTION","Participants will rinse their mouth with room-temperature water at approximately 30-35°C, with identical frequency and duration as the experimental arm.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"BEHAVIORAL","Water Rinse at Different Temperatures","rinse their mouth with cold water at approximately 15-20°C",[9],[26],{"name":27,"role":28,"phone":29,"phoneExt":18,"email":30},"Yueh-Chun Lee, MD-PhD","CONTACT","+886937355888","lee.yuehchun@gmail.com",[32],{"facility":5,"status":18,"city":33,"state":34,"zip":18,"country":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":18},"Taichung","Taiwan (r.o.c.)","Taiwan",{"type":37,"coordinates":38},"Point",[39,40],120.6839,24.1469,{"lat":40,"lon":39},{"type":43,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100612359",false,"NCT07252557","Mouthwash Temperature and Oral Mucositis in Head and Neck Radiotherapy","Effectiveness of Different Mouthwash Temperatures on Oral Mucositis Pain and Patient Comfort During Radiotherapy for Head and Neck Cancer: A Randomized Controlled Trial","CoolRinseHNC","Inclusion Criteria:\n\n* Histologically confirmed head and neck cancer (HNC) receiving radiotherapy for the first time, with or without concurrent chemotherapy.\n* Conscious, communicative, and able to perform the rinsing procedure and complete questionnaires.\n* Provided written informed consent prior to enrollment.\n\nExclusion Criteria:\n\n* Non-HNC diagnoses or radiotherapy to sites outside the oral\u002Foropharyngeal region.\n* Cognitive impairment or inability to complete the rinsing protocol.","ALL","20 Years","80 Years",{"count":55,"type":56},200,"ESTIMATED","INTERVENTIONAL",[59],"NA","This single-center randomized controlled trial evaluates the effects of cold (15-20°C) versus room-temperature (30-35°C) water gargling on oral mucositis severity, pain, and comfort in patients with head and neck cancer undergoing radiotherapy. Participants will rinse their mouth four times daily for 30-60 seconds over a 6-week radiotherapy course, with follow-up for two additional weeks. The study hypothesizes that cold-water rinsing can reduce the severity of radiation-induced oral mucositis (RTOM) and pain, improve oral comfort, and minimize treatment interruptions.",[62,63,64,65,66],"Head and Neck Cancer (H&Amp;Amp;N)","Radiation-induced Oral Mucositis","Supportive Care","Nursing Interventions","Radiotherapy Side Effects",[68,69,70,9,64,71,72,73],"Head and Neck Cancer","Radiation-Induced Oral Mucositis","Water Temperature","Pain Management","Radiotherapy","Nursing Intervention","NOT_YET_RECRUITING","2025-11-24",{"date":77,"type":78},"2025-11-26","ACTUAL",{"date":80,"type":56},"2026-01-01",{"date":82,"type":56},"2027-03-31",{"name":5,"class":6},1]