[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100571489":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":29,"locations":35,"responsibleParty":52,"collaborators":11,"id":56,"slug":11,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":57,"sex":63,"minAge":11,"maxAge":11,"enrollmentInfo":64,"targetDuration":11,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":37,"whyStopped":11,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Beijing Tiantan Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Open Surgery (anterior temporal lobectomy, ATL)","EXPERIMENTAL",null,[13],"Procedure: Open Surgery",{"label":15,"type":16,"description":11,"interventionNames":17},"Minimally Invasive Surgery (MRgLITT)","ACTIVE_COMPARATOR",[18],"Procedure: Resonance-guided Laser Interstitial Thermal Therapy (MRgLITT)",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"PROCEDURE","Resonance-guided Laser Interstitial Thermal Therapy (MRgLITT)","MRgLITT employs laser energy delivered through a stereotactically placed laser applicator to precisely ablate the epileptogenic tissue.",[15],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"Open Surgery","Traditional Open Surgery",[9],[30],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},"Kai Zhang, Dr.","CONTACT","86 01059975051","zhangkai62035@sina.com",[36],{"facility":5,"status":37,"city":38,"state":39,"zip":40,"country":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"RECRUITING","Beijing","Beijing Municipality","100070","China",{"type":43,"coordinates":44},"Point",[45,46],116.39723,39.9075,{"lat":46,"lon":45},[49],{"name":50,"role":32,"phone":33,"phoneExt":11,"email":51},"Jiajie Mo, Dr.","jiajiemo@foxmail.com",{"type":53,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Kai Zhang","Dr.","100571489",false,"NCT06720922","MRgLITT for mTLE: A PROBE Trial","Magnetic Resonance-guided Laser Interstitial Thermal Therapy for Mesial Temporal Lobe Epilepsy: A Prospective, Randomized, Open Blinded, End-point Trial","MINE","Inclusion Criteria:\n\n* 18-65 years.\n* Drug-resistant mesial temporal lobe epilepsy.\n* Seizure frequency ≥ 1 time \u002Fmonth.\n* Participants approved.\n\nExclusion Criteria:\n\n* History of brain surgery.\n* Intracranial space occupying lesions.\n* Individuals with significant medical comorbidities or conditions that pose an excessive risk for surgery, such as severe cardiovascular disease, respiratory disorders, or uncontrolled systemic infections.","ALL",{"count":65,"type":66},120,"ESTIMATED","INTERVENTIONAL",[69],"NA","How does magnetic resonance-guided laser interstitial thermal therapy (MRgLITT) impact clinical prognosis in mesial temporal lobe epilepsy (mTLE)?",[72],"Temporal Lobe Epilepsy (TLE)",[74,26,75],"Magnetic Resonance-guided Laser Interstitial Thermal Therapy","Temporal Lobe Epilepsy","2026-01-19",{"date":78,"type":79},"2026-01-21","ACTUAL",{"date":81,"type":79},"2025-07-21",{"date":83,"type":66},"2028-01-01",{"name":5,"class":6},1]