[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100201911":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":16,"studyPopulation":17,"armGroups":18,"interventions":13,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":286,"collaborators":13,"id":288,"slug":13,"hasResults":289,"nctId":290,"briefTitle":291,"officialTitle":292,"acronym":293,"eligibilityCriteria":294,"healthyVolunteers":289,"sex":295,"minAge":13,"maxAge":13,"enrollmentInfo":296,"targetDuration":299,"studyType":300,"phases":13,"briefSummary":301,"conditions":302,"keywords":304,"overallStatus":112,"whyStopped":13,"lastUpdateSubmitDate":309,"lastUpdatePostDateStruct":310,"startDateStruct":313,"completionDateStruct":315,"leadSponsor":317,"locationsCount":318},{"fullName":5,"class":6},"Baylor Research Institute","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Target Limb Revascularization","Target Lesion or Vessel Revascularization or Surgical Revascularization\u002FAmputation of Target Limb","12 months",null,{"allocation":13,"interventionModel":13,"interventionModelDescription":13,"primaryPurpose":13,"observationalModel":15,"timePerspective":6,"maskingInfo":13},"COHORT","Patients undergoing an endovascular intervention receiving either stents or percutaneous transluminal angioplasty (PTA) to the superficial femoral, popliteal, peroneal, anterior tibial, or posterior tibial arteries will be entered into this registry. Patients undergoing treatment of the external or common iliac arteries are not admissible to the registry, unless these arteries were treated in addition to one of the five aforementioned arteries. The registry will collect data in the form of patient background information, procedural data, and follow-up data from the patient's medical records. Data available since Jan 1 2005 will be included in the registry, until 14,000 patients have been included. The data will be entered into a software, REDCAP, that automatically provides data quality verification and processing.\n\nSpecifically, the data fields collected by the registry will be:\n\nI) Background Information\n\n1. Site, attending operator, and month-year of procedure\n2. Patient height, weight, age, race, and sex\n3. Rutherford claudication category, left and right ankle brachial index, ambulatory status, claudication free distance\n4. Risk factors such as diabetes, hypertension, hyperlipidemia, and prior history of lower extremity percutaneous intervention\n5. Patient comorbidities such as coronary artery disease, congestive heart failure, prior myocardial infarction, stroke, transient ischemic attack, chronic kidney disease, and other.\n\nII) Lesion Characteristics (enter data for up to five lesions)\n\n1. Access site relative to target limb, sheath size, target limb (left or right)\n2. Target vessel: superficial femoral artery, popliteal artery, peroneal artery, anterior tibial artery, or posterior tibial artery\n3. Which, if any, Iliac arteries were treated during procedure\n4. Target lesion location (ostial, proximal, medial, distal), estimated vessel diameter, estimated vessel length\n5. Lesion characteristics (heavily calcified, diffuse, thrombus, chronic total occlusion (CTO), in-stent restenosis, restenosis post balloon angioplasty, profunda femoris disease)\n6. Planned revascularization strategy: stent or non-stent based\n\nIIa) CTO Characteristics (Only required for CTO lesions)\n\n1. Type of proximal and distal stumps, sidebranches present, collateral filling of distal vessel, tortuosity, prior attempt to cross CTO\n2. Antegrade or retrograde crossing strategy, crossing technique, number of attempts\n3. Crossing devices used, microcatheters used, sub-intimal re-entry devices used (if any), embolic protection device used\n\nIII) Intervention Details\n\n1. Atherectomy device used (Cutting Balloon, TurboHawk, SilverHawk, Rotablator, Laser)\n2. Pre and post-dilation balloon information (type, length, width, average atmospheric pressure, number of inflations)\n3. Stent information (indication for stents, length, width, maximum pressure, overlapping with previous stents)\n4. Aspiration\u002FThrombectomy used, thrombolytic therapy used\n5. Percent change in stenosis and TIMI flows (before and after)\n\nIV) Outcomes\n\n1. Technical success (\\\u003C30% residual stenosis), procedural success (\\\u003C30% residual stenosis without complications), and case comments\n2. Anti-coagulation used, medical therapy (plavix, aspirin, lipid lowering therapy, angiotensin receptor blocker, beta blocker, cilostazol, trental, insulin, oral hypoglycemics)\n3. Duration of procedure, fluoroscopy (amount used, type, and time)\n4. Any procedural complications\n\nV) Follow-Up\n\n1. Month and year of follow-up\n2. Rutherford category, left and right ankle brachial index, claudication-free distance, ambulatory status, change in claudication (improved, same, or worsened)\n3. Duplex ultrasound performed\n4. Adverse events experienced (death, myocardial infarction, stroke, stent thrombosis, stent fracture, angiography, repeat endovascular intervention, surgical revascularization, amputation in target or non-target limb)\n\nFollow-up data is recorded from clinical visits six and twelve months after the procedure. If the patient undergoes a repeat intervention on the target limb, a new record is created for the procedure.","Patients with diagnosed peripheral arterial disease who underwent endovascular intervention, and received either a stent or non-stent based treatment.",[19,22],{"label":20,"type":13,"description":21,"interventionNames":13},"Stent","The patient received one or more stents to the superficial femoral, popliteal, peroneal, anterior tibial, or posterior tibial arteries in AT LEAST one of the lesions treated during the course of the procedure.",{"label":23,"type":13,"description":24,"interventionNames":13},"Non-Stent","The patient did not receive a stent to the superficial femoral, popliteal, peroneal, anterior tibial, or posterior tibial arteries in ANY of the lesions treated during the course of the procedure.",[26],{"name":27,"affiliation":5,"role":28},"Subhash Banerjee, MD","PRINCIPAL_INVESTIGATOR",[30],{"name":31,"role":32,"phone":33,"phoneExt":13,"email":34},"David Fernandez Vazquez, MD","CONTACT","2148202928","david.fernandezvazquez@bswhealth.org",[36,50,60,70,80,90,100,110,124,134,144,157,166,176,182,192,205,223,229,238,250,259,268,277],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":13},"Arkansas Heart Institute","COMPLETED","Little Rock","Arkansas","72211","United States","US",{"type":45,"coordinates":46},"Point",[47,48],-92.28959,34.74648,{"lat":48,"lon":47},{"facility":51,"status":38,"city":52,"state":53,"zip":54,"country":42,"countryCode":43,"cosmosGeoPoint":55,"geoPoint":59,"contacts":13},"Denver VAMC","Denver","Colorado","80220",{"type":45,"coordinates":56},[57,58],-104.9847,39.73915,{"lat":58,"lon":57},{"facility":61,"status":38,"city":62,"state":63,"zip":64,"country":42,"countryCode":43,"cosmosGeoPoint":65,"geoPoint":69,"contacts":13},"Emory University","Atlanta","Georgia","30322",{"type":45,"coordinates":66},[67,68],-84.38798,33.749,{"lat":68,"lon":67},{"facility":71,"status":38,"city":72,"state":73,"zip":74,"country":42,"countryCode":43,"cosmosGeoPoint":75,"geoPoint":79,"contacts":13},"Loyola University Medical Center","Chicago","Illinois","60153",{"type":45,"coordinates":76},[77,78],-87.65005,41.85003,{"lat":78,"lon":77},{"facility":81,"status":38,"city":82,"state":83,"zip":84,"country":42,"countryCode":43,"cosmosGeoPoint":85,"geoPoint":89,"contacts":13},"Indiana University Health Ball Memorial Hospital","Muncie","Indiana","47303",{"type":45,"coordinates":86},[87,88],-85.38636,40.19338,{"lat":88,"lon":87},{"facility":91,"status":38,"city":92,"state":93,"zip":94,"country":42,"countryCode":43,"cosmosGeoPoint":95,"geoPoint":99,"contacts":13},"Mid West Cardiovascular Research Foundation","Davenport","Iowa","52803",{"type":45,"coordinates":96},[97,98],-90.57764,41.52364,{"lat":98,"lon":97},{"facility":101,"status":38,"city":102,"state":103,"zip":104,"country":42,"countryCode":43,"cosmosGeoPoint":105,"geoPoint":109,"contacts":13},"VA Boston Healthcare System","Boston","Massachusetts","02301",{"type":45,"coordinates":106},[107,108],-71.05977,42.35843,{"lat":108,"lon":107},{"facility":111,"status":112,"city":113,"state":114,"zip":115,"country":42,"countryCode":43,"cosmosGeoPoint":116,"geoPoint":120,"contacts":121},"Detroit Medical Center","RECRUITING","Detroit","Michigan","48201",{"type":45,"coordinates":117},[118,119],-83.04575,42.33143,{"lat":119,"lon":118},[122],{"name":123,"role":28,"phone":13,"phoneExt":13,"email":13},"Chadi Alraies, MD",{"facility":125,"status":38,"city":126,"state":127,"zip":128,"country":42,"countryCode":43,"cosmosGeoPoint":129,"geoPoint":133,"contacts":13},"St. Louis University Medical Center","St Louis","Missouri","63104",{"type":45,"coordinates":130},[131,132],-90.19789,38.62727,{"lat":132,"lon":131},{"facility":135,"status":38,"city":136,"state":137,"zip":138,"country":42,"countryCode":43,"cosmosGeoPoint":139,"geoPoint":143,"contacts":13},"Carolina East Health System","New Bern","North Carolina","28560",{"type":45,"coordinates":140},[141,142],-77.04411,35.10849,{"lat":142,"lon":141},{"facility":145,"status":112,"city":146,"state":147,"zip":148,"country":42,"countryCode":43,"cosmosGeoPoint":149,"geoPoint":153,"contacts":154},"Cleveland Clinic","Cleveland","Ohio","38732",{"type":45,"coordinates":150},[151,152],-81.69541,41.4995,{"lat":152,"lon":151},[155],{"name":156,"role":28,"phone":13,"phoneExt":13,"email":13},"Aravinda Nanjundappa, MD",{"facility":158,"status":112,"city":146,"state":147,"zip":159,"country":42,"countryCode":43,"cosmosGeoPoint":160,"geoPoint":162,"contacts":163},"Harrington Heart and Vascular Institute, University Hospitals","44106",{"type":45,"coordinates":161},[151,152],{"lat":152,"lon":151},[164],{"name":165,"role":28,"phone":13,"phoneExt":13,"email":13},"Mehdi Shishehbor, MD",{"facility":167,"status":38,"city":168,"state":169,"zip":170,"country":42,"countryCode":43,"cosmosGeoPoint":171,"geoPoint":175,"contacts":13},"Oklahoma University Health Science Center","Oklahoma City","Oklahoma","73104",{"type":45,"coordinates":172},[173,174],-97.51643,35.46756,{"lat":174,"lon":173},{"facility":177,"status":38,"city":168,"state":169,"zip":178,"country":42,"countryCode":43,"cosmosGeoPoint":179,"geoPoint":181,"contacts":13},"Integris Heart Hospital","73109",{"type":45,"coordinates":180},[173,174],{"lat":174,"lon":173},{"facility":183,"status":38,"city":184,"state":185,"zip":186,"country":42,"countryCode":43,"cosmosGeoPoint":187,"geoPoint":191,"contacts":13},"Albert Einstein Healthcare Network","Philadelphia","Pennsylvania","19141",{"type":45,"coordinates":188},[189,190],-75.16362,39.95238,{"lat":190,"lon":189},{"facility":193,"status":112,"city":194,"state":195,"zip":196,"country":42,"countryCode":43,"cosmosGeoPoint":197,"geoPoint":201,"contacts":202},"Wellmont CVA Heart Institute","Kingsport","Tennessee","37663",{"type":45,"coordinates":198},[199,200],-82.56182,36.54843,{"lat":200,"lon":199},[203],{"name":204,"role":28,"phone":13,"phoneExt":13,"email":13},"Gaurav Rana, MD",{"facility":206,"status":112,"city":207,"state":208,"zip":209,"country":42,"countryCode":43,"cosmosGeoPoint":210,"geoPoint":214,"contacts":215},"Seton Heart Institute\u002F UT Austin","Austin","Texas","78705",{"type":45,"coordinates":211},[212,213],-97.74306,30.26715,{"lat":213,"lon":212},[216,221],{"name":217,"role":32,"phone":218,"phoneExt":219,"email":220},"Sarah J Benedict","512-324-9999","18171","sarah.benedict@ascension.org",{"name":222,"role":28,"phone":13,"phoneExt":13,"email":13},"Peter Monteleone, MD",{"facility":224,"status":38,"city":207,"state":208,"zip":225,"country":42,"countryCode":43,"cosmosGeoPoint":226,"geoPoint":228,"contacts":13},"Cardiothoracic and Vascular Surgeons","78756",{"type":45,"coordinates":227},[212,213],{"lat":213,"lon":212},{"facility":230,"status":38,"city":231,"state":208,"zip":232,"country":42,"countryCode":43,"cosmosGeoPoint":233,"geoPoint":237,"contacts":13},"Christus Sphon Hospital Corpus Christi-Shoreline","Corpus Christi","78404",{"type":45,"coordinates":234},[235,236],-97.39638,27.80058,{"lat":236,"lon":235},{"facility":239,"status":112,"city":240,"state":208,"zip":241,"country":42,"countryCode":43,"cosmosGeoPoint":242,"geoPoint":246,"contacts":247},"North Texas Veteran Affairs Medical Center","Dallas","75216",{"type":45,"coordinates":243},[244,245],-96.80667,32.78306,{"lat":245,"lon":244},[248],{"name":249,"role":28,"phone":13,"phoneExt":13,"email":13},"Shirling Tsai, MD",{"facility":251,"status":112,"city":240,"state":208,"zip":252,"country":42,"countryCode":43,"cosmosGeoPoint":253,"geoPoint":255,"contacts":256},"Baylor Scott & White Research Institute","75226",{"type":45,"coordinates":254},[244,245],{"lat":245,"lon":244},[257,258],{"name":31,"role":32,"phone":13,"phoneExt":13,"email":13},{"name":27,"role":28,"phone":13,"phoneExt":13,"email":13},{"facility":260,"status":38,"city":261,"state":208,"zip":262,"country":42,"countryCode":43,"cosmosGeoPoint":263,"geoPoint":267,"contacts":13},"El Paso Cardiovascular Care","El Paso","79925",{"type":45,"coordinates":264},[265,266],-106.48693,31.75872,{"lat":266,"lon":265},{"facility":269,"status":38,"city":270,"state":208,"zip":271,"country":42,"countryCode":43,"cosmosGeoPoint":272,"geoPoint":276,"contacts":13},"North Dallas Research Associates","McKinney","75069",{"type":45,"coordinates":273},[274,275],-96.61527,33.19762,{"lat":275,"lon":274},{"facility":278,"status":38,"city":279,"state":208,"zip":280,"country":42,"countryCode":43,"cosmosGeoPoint":281,"geoPoint":285,"contacts":13},"UT Health Sciences Center","San Antonio","78229",{"type":45,"coordinates":282},[283,284],-98.49363,29.42412,{"lat":284,"lon":283},{"type":287,"investigatorFullName":13,"investigatorTitle":13,"investigatorAffiliation":13,"oldNameTitle":13,"oldOrganization":13},"SPONSOR","100201911",false,"NCT01904851","Multi-Center Registry for Peripheral Arterial Disease Interventions and Outcomes","Multi-Center Registry Comparing Stent and Non-Stent Based Interventional Outcomes for Patients With Peripheral Arterial Disease","XLPAD","Inclusion Criteria:\n\n* Underwent Endovascular Intervention\n* Treated Iliac, Common or Superficial Femoral, Popliteal, Peroneal, Anterior Tibial, or Posterior Tibial Arteries\n\nExclusion Criteria:\n\n* Surgical Bypass","ALL",{"count":297,"type":298},14000,"ESTIMATED","12 Months","OBSERVATIONAL","XLPAD is an observational study designed to evaluate the effectiveness and use of stent and non-stent based therapies among PAD patients. The study will create a registry that will include entry of procedural and clinical follow-up information into an online data collection software, REDCAP.Data available since Jan 1 2005 will be included in the registry, until 14,000 patients have been included. The primary objectives of this observational registry study are to:\n\n1. Compare stent and non-stent based outcomes defined as a composite of symptom driven target vessel revascularization (TVR), unplanned surgical revascularization of the target limb and need for target limb amputation through 12 months post-index procedure (Primary efficacy endpoint)\n2. Compare stent and non-stent based outcomes defined as a composite of causes such as: death, myocardial infarction (MI), stroke, peri-procedural complications, target vessel revascularization (TVR) and unplanned surgical revascularization\u002Famputation of the target limb through 12 months (Primary safety endpoint)\n3. Compare stent and non-stent based change in walking distance, Rutherford category and\u002For ankle- brachial index (ABI) at 12 months compared to baseline (Primary clinical improvement endpoint)\n\nApproximately 14,000patients will be enrolled at approximately 60 sites worldwide. Enrollment in the observational study will be monitored in an effort to achieve at least 20% (and no more than 80%) of the population receiving stents as the initial treatment strategy. Follow-up visits by sites will be reported at 6 and 12 months after index procedure to collect data on treatment patterns and effectiveness, and outcomes. The follow-up procedures are not mandated by the registry protocol. Each site will be encouraged to enter follow-up information derived from clinically indicated follow-up visits. All events post-index procedure till the 7th month will be reported under the 6 month follow-up form and subsequent follow-up till the 13th month post-procedure will be entered on the 12 month follow-up form.\n\nPatient management and treatment decisions are at the discretion of the care team per routine clinical practice. The procedural aspects (including selection of stent type or non-stent based treatments) and follow-up are not mandated by the registry and will be up to the discretion of the operator and\u002For based upon the practice dictated by the clinical care of the patient. Therefore the study poses minimal risk to the patient.",[303],"Peripheral Arterial Disease",[303,305,306,307,308],"Stents","Registry","Angioplasty","Endovascular Procedures","2026-02-04",{"date":311,"type":312},"2026-02-06","ACTUAL",{"date":314,"type":13},"2013-01",{"date":316,"type":298},"2033-01",{"name":5,"class":6},24]