Multicenter Cohort Study of ESD and Chemo-radiotherapy for High-risk Early-stage Esophageal Cancer

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-75
SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University

About this trial

This multicenter, prospective observational cohort study has the potential to optimize individualized chemoradiotherapy regimen for early-stage esophageal cancer patients who have received endoscopic submucosal dissection.

Eligibility criteria

Qualifiers

1. Esophageal cancer patients who are pathologically confirmed as pT1a-MM stage or pT1b stage after endoscopic submucosal dissection; 2. No definite contraindications for chemo-radiotherapy; 3. Informed consent has been signed; 4. Refused surgery after endoscopic submucosal dissection.

Disqualifiers

1. Severe heart, brain, lung disease or renal dysfunction; 2. Previous history of other malignancies; 3. Prior radiation or chemotherapy 4. Researchers consider it inappropriate to participate in this experiment

Trial design

Treatments tested in this trial

  • chemo-radiation

Treatment groups

120 Participants
are divided into 3 treatment groups

Locations

2
The Second Affiliated Hospital of Zhejiang University School of Medicine310000, HangzhouZhejiang, China
The Second Affiliated Hospital of Zhejiang University, School of Medicine Hangzhou China

Sponsors and collaborators

Second Affiliated Hospital, School of Medicine, Zhejiang University

Lead sponsor