This observational study aims to evaluate multiple dimensions of health in patients with Obstructive Sleep Apnea Syndrome (OSAS), before and after three weeks of ventilotherapy.
Specifically, the study aims to identify pre- vs post-treatment differences in the following domains:
* cognitive performance * blood expression of biomarkers related to neurodegeneration * psychosocial wellbeing
Thus, patients will complete the following evaluations before (T0) and after (T1) ventilotherapy:
* neuropsychological standard assessment * blood sampling * psychosocial self-reported questionnaires
OSAS diagnosis (AHI > 5)
handedness: right
previous ventilotherapy
neurological and/or neurodegenerative conditions
Personality disorders, autism spectrum disorders, schizophrenia, psychosis
sleep disorders comorbidities (eg., narcolepsy)
Istituto Auxologico Italiano
Lead sponsor