[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100630488":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":22,"centralContacts":26,"locations":34,"responsibleParty":51,"collaborators":10,"id":53,"slug":10,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":10,"eligibilityCriteria":57,"healthyVolunteers":54,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":10,"studyType":64,"phases":10,"briefSummary":65,"conditions":66,"keywords":68,"overallStatus":37,"whyStopped":10,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Benign thyroid nodule",null,"Confirmed by histopathology.",[13],"Other: Histopathology or cytopathology.",{"label":15,"type":10,"description":11,"interventionNames":16},"Malignant thyroid nodule",[13],[18],{"type":6,"name":19,"description":20,"armGroupLabels":21,"otherNames":10},"Histopathology or cytopathology.","This is a observation stufy.",[9,15],[23],{"name":24,"affiliation":5,"role":25},"Jingliang Ruan, Ph.D.","PRINCIPAL_INVESTIGATOR",[27,31],{"name":24,"role":28,"phone":29,"phoneExt":10,"email":30},"CONTACT","+8613694202230","ruanjl3@mail.sysu.edu.cn",{"name":32,"role":28,"phone":33,"phoneExt":10,"email":10},"Xinmin Xiao, B.S.","+8618420058253",[35],{"facility":36,"status":37,"city":38,"state":38,"zip":39,"country":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"No. 33 Yingfeng Road, Haizhu District, Guangzhou City, Guangdong Province, Sun Yat-sen Memorial Hospital","RECRUITING","Guangzhou","510288","China",{"type":42,"coordinates":43},"Point",[44,45],113.25,23.11667,{"lat":45,"lon":44},[48,49],{"name":24,"role":28,"phone":29,"phoneExt":10,"email":30},{"name":32,"role":28,"phone":33,"phoneExt":10,"email":50},"1124507651@qq.com",{"type":52,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100630488",false,"NCT07488325","Multimodal Assessment of Malignancy in Atypia of Undetermined Significance in Thyroid Nodules Using Ultrasound and Cytology Whole-Slide Images","Inclusion Criteria:\n\n* (a) Patients who underwent fine-needle aspiration of thyroid nodules and received a cytological diagnosis of Bethesda Ⅲ.\n* (b) Patients who subsequently underwent thyroid surgery with a definitive histopathological diagnosis of benign or malignant lesions,.\n* (c) Availability of at least one ultrasound image acquired prior to surgery.\n\nExclusion Criteria:\n\n* (a) Patients without confirmation by surgical pathology,.\n* (b) Patients without any available or usable ultrasound images.","ALL","18 Years","80 Years",{"count":62,"type":63},396,"ESTIMATED","OBSERVATIONAL","The prospective study aim to develop a multimodal deep learning model that integrates ultrasound images and cytological whole-slide images for more accurate malignant risk prediction of Bethesda III thyroid nodules.",[67],"Thyroid Nodule",[67,69,70,71,72],"Atypia of Undetermined Significance","Multimodal Deep Learning","Ultrasound","Cytology Whole-Slide Image","2026-03-30",{"date":75,"type":76},"2026-04-01","ACTUAL",{"date":78,"type":76},"2026-03-01",{"date":80,"type":63},"2026-07-15",{"name":5,"class":6},1]