[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100397913":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":38,"responsibleParty":57,"collaborators":60,"id":66,"slug":18,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":67,"sex":73,"minAge":74,"maxAge":18,"enrollmentInfo":75,"targetDuration":18,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":85,"overallStatus":41,"whyStopped":18,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Insel Gruppe AG, University Hospital Bern","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention","EXPERIMENTAL","Patients that meet the inclusion criteria will be randomised and scheduled for surgery at least 2 weeks after the diagnosis\u002Fdecision to proceed to surgery. This timeframe allows the implementation of a minimal 2 weeks (up to 4 weeks) multidisciplinary prehabilitation program. Prehabilitation program is composed of 4 elements: exercise training, nutritional intervention, correction of anaemia and smoking cessation. An individual treatment strategy will be proposed to the patient by a multidisciplinary team consisting of surgeon, anesthesiologist, dietitian and physiotherapist.",[13],"Procedure: Multimodal Prehabilitation",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","NO_INTERVENTION","Perioperative care of the control group will be based on standardized, multi-element, ERAS recommendations as already implemented in the different participating clinics.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"PROCEDURE","Multimodal Prehabilitation","A multimodal prehabilitation program (exercise, nutrition, anemia correction and smoking cessation).",[9],[26],{"name":27,"affiliation":28,"role":29},"Dominique A Engel, Dr","Department of Anaesthesiology and Pain Therapy, University Hospital Bern","PRINCIPAL_INVESTIGATOR",[31,35],{"name":27,"role":32,"phone":33,"phoneExt":18,"email":34},"CONTACT","0041316322111","dominique.engel@insel.ch",{"name":36,"role":32,"phone":33,"phoneExt":18,"email":37},"Patrick Wuethrich, Prof","patrick.wuethrich@insel.ch",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Department of Anaesthesiology and Pain Therapy, University Hospital Bern Inselspital Bern","RECRUITING","Bern","Canton of Bern","3010","Switzerland",{"type":47,"coordinates":48},"Point",[49,50],7.44744,46.94809,{"lat":50,"lon":49},[53,55],{"name":27,"role":32,"phone":54,"phoneExt":18,"email":34},"00316322111",{"name":36,"role":32,"phone":56,"phoneExt":18,"email":37},"00416322111",{"type":29,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Dominique Engel","Dr.med.",[61,63],{"name":62,"class":6},"University of Bern",{"name":64,"class":65},"Department of clinical research, Bern","UNKNOWN","100397913",false,"NCT04461301","Multimodal Prehabilitation for Surgery in the Elderly: a Randomised, Prospective, Multicenter, Multidisciplinary Trial","Multimodal Prehabilitation for Major Surgery in Elderly Patients to Lower Complications and to Increase Cost Effectiveness: a Randomised, Prospective, Multicenter, Multidisciplinary Trial (PREHABIL Trial).","PREHABIL","Inclusion Criteria:\n\n* Written informed consent\n* comorbid (≥ASA 3)\n* pre-existing fitness deficit: AT\\\u003C11ml\u002Fkg\u002Fmin respectively VO2peak\\\u003C14ml\u002Fkg\u002Fmin if AT unavailable or VE\u002FVCO2 slope \\> 33\n* scheduled for major urologic, thoracic, visceral, orthopaedic or cardiovascular surgery\n* screening at least 2 weeks prior to surgery\n\nExclusion Criteria:\n\n* Paralysis or patients with mobility problems (who are unable to exercise),\n* Premorbid conditions or orthopaedic impairments that contraindicate exercise,\n* Cognitive disabilities,\n* Chronic renal failure (need for dialysis)\n* Emergency procedures.","ALL","65 Years",{"count":76,"type":77},466,"ESTIMATED","INTERVENTIONAL",[80],"NA","This multicentric, randomised controlled trial is to the investigators knowledge the first implementation of a multimodal, multidisciplinary prehabilitation approach using knowledge from different specialties to lower complications and to increase cost effectiveness after major surgery in elderly, frail patients.",[83,84],"Frail Elderly Syndrome","Major Surgery",[86],"Comprehensive Complication Index","2024-10-29",{"date":89,"type":90},"2024-11-01","ACTUAL",{"date":92,"type":90},"2022-02-01",{"date":94,"type":77},"2026-12-30",{"name":5,"class":6},1]