[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100612269":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":25,"centralContacts":34,"locations":40,"responsibleParty":71,"collaborators":75,"id":79,"slug":20,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":20,"eligibilityCriteria":84,"healthyVolunteers":85,"sex":86,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":20,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":100,"overallStatus":43,"whyStopped":20,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"Universite de Picardie Jules Verne","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Prior Experience Group","EXPERIMENTAL","Participants in this arm have experienced capsaicin cream before and will be given a neutral cream. They will be told that the cream contains capsaicin and will cause pain.",[13,14],"Other: Pain expectation conditioning","Other: Gait assesment",[16,21],{"type":6,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"Pain expectation conditioning","Participants receive a neutral cream with no real harmful effects with verbal and behavioral suggestions that it may cause localized pain. Researchers wear gloves during application and emphasize the potential discomfort, stating effects may intensify with movement.",[9],null,{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":20},"Gait assesment","Gait will be assessed both before and after cream application. Each assessment will consist of walking on a treadmill at varying speeds while physiological data (EMG) is recorded. Identical questionnaires (VAS, TAMPA, and PCS) will be administered immediately following the first gait assessment.",[9],[26,30,32],{"name":27,"affiliation":28,"role":29},"Thierry Lelard, PhD, HDR","Lecturer","STUDY_DIRECTOR",{"name":31,"affiliation":28,"role":29},"Maryne Cozette, PhD, Lecturer",{"name":33,"affiliation":28,"role":29},"Guillaume Léonard, PhD, Lecturer",[35],{"name":36,"role":37,"phone":38,"phoneExt":20,"email":39},"Jennifer Burgos-Tirado, M.Sc.A., Ing.","CONTACT","+33 7 71 27 11 35","jennifer.burgos.tirado@u-picardie.fr",[41,57],{"facility":42,"status":43,"city":44,"state":20,"zip":20,"country":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Centre de Recherche sur le Vieillissement","RECRUITING","Sherbrooke","Canada",{"type":47,"coordinates":48},"Point",[49,50],-71.89908,45.40008,{"lat":50,"lon":49},[53],{"name":54,"role":37,"phone":55,"phoneExt":20,"email":56},"Guillaume Léonard, PhD","819-829-7131","guillaume.leonard2@usherbrooke.ca",{"facility":58,"status":43,"city":59,"state":20,"zip":20,"country":60,"cosmosGeoPoint":61,"geoPoint":65,"contacts":66},"Université de Picardie Jules Verne","Amiens","France",{"type":47,"coordinates":62},[63,64],2.3,49.9,{"lat":64,"lon":63},[67],{"name":68,"role":37,"phone":69,"phoneExt":20,"email":70},"Said Ahmaidi","+33 3 22 82 74 41","said.ahmaidi@u-picardie.fr",{"type":72,"investigatorFullName":73,"investigatorTitle":74,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"PRINCIPAL_INVESTIGATOR","Jennifer Burgos Tirado","Researcher - Ph.D student",[76],{"name":77,"class":78},"Mitacs","INDUSTRY","100612269",false,"NCT07251387","Muscle Synergies in Pain and Pain Anticipation","Test-retest Fidelity of a Tool for Calculation of Muscle Synergies","Inclusion Criteria:\n\n* Aged 18-35 years old\n* Healthy participant with no self-reported diagnosed neurological, musculoskeletal, or cardiovascular disorders\n* Body Mass Index (BMI) \\\u003C 30\n* Ability to walk unaided for at least 10 minutes without major physical limitations\n\nExclusion Criteria:\n\n* Presence of pain at the time of testing\n* Self-reported diagnosed condition affecting mobility\n* Known allergy to any component of the study cream\n* Allergy to EMG electrode adhesives\n* Inability to stand unassisted for more than 1 minute\n* Inability to walk\u002Frun at the required speed and distance\n* Weight exceeding 150 kg (due to treadmill limitations)\n* Recent intake (prior intervention) of:\n* Analgesics (within 6 hours)\n* Cigarettes (within 6 hours)\n* Caffeine (within 2 hours)\n* Skin lesions at the cream application site\n* Pregnancy\n* Failure to understand instructions\n* Daytime pain reported by participant on day of experimentation",true,"ALL","18 Years","35 Years",{"count":90,"type":91},12,"ESTIMATED","INTERVENTIONAL",[94],"NA","This study investigates how the anticipation of pain affects muscle synergies. One group will be recruited who will first experience actual pain from capsaicin cream and are then presented with a harmless cream deceptively labeled as capsaicin. The changes in muscle synergies will be measured during walking tasks.",[97,98,99],"Pain","Nocebo Effect","Pain Anticipation",[101,102,97,103,104,105],"Nocebo effect","Pain anticipation","Gait","Motricity","Muscle synergies","2026-06-08",{"date":108,"type":109},"2026-06-11","ACTUAL",{"date":111,"type":109},"2026-01-01",{"date":113,"type":91},"2027-10-01",{"name":5,"class":6},2]