[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100587528":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":35,"centralContacts":42,"locations":48,"responsibleParty":68,"collaborators":26,"id":71,"slug":26,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":77,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":26,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":91,"overallStatus":51,"whyStopped":26,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Universite de Picardie Jules Verne","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Nocebo Conditioning Group","EXPERIMENTAL","Participants in this arm will receive the neutral cream with instructions suggesting it may cause pain.",[13,14],"Other: Pain expectation conditioning","Other: Intervention: Gait",{"label":16,"type":17,"description":18,"interventionNames":19},"Control Group","PLACEBO_COMPARATOR","Participants receive application of identical neutral cream with verbal and behavioral suggestions that it may cause localized pain, creating a nocebo effect through expectation manipulation.",[20,14],"Other: Comparator (Control Group)",[22,27,31],{"type":6,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"Pain expectation conditioning","Participants receive application of a neutral cream (MEDICAFARM) with verbal and behavioral suggestions that it may cause localized pain. Researchers wear gloves during application and emphasize potential discomfort, stating effects may intensify with movement.",[9],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Comparator (Control Group)","Participants receive identical application of the neutral cream but are informed it is inert and harmless. Researchers apply the cream without gloves and provide neutral instructions.",[16],{"type":6,"name":32,"description":33,"armGroupLabels":34,"otherNames":26},"Intervention: Gait","Participants undergo assessment procedures including:\n\n* Pre- and post-application gait analysis (GAITRite mat, Zebris treadmill)\n* Physiological monitoring (EMG, HRV, EDA)\n* Identical questionnaires (BPI, TSK, FACS, PCS, VAS)",[16,9],[36,40],{"name":37,"affiliation":38,"role":39},"Thierry Lelard, PhD","Lecturer","STUDY_DIRECTOR",{"name":41,"affiliation":38,"role":39},"Maryne Cozette, PhD",[43],{"name":44,"role":45,"phone":46,"phoneExt":26,"email":47},"Jennifer Burgos-Tirado, Master","CONTACT","07 71 27 11 35","jennifer.burgos.tirado@u-picardie.fr",[49],{"facility":50,"status":51,"city":52,"state":26,"zip":26,"country":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Université de Picardie Jules Verne","RECRUITING","Amiens","France",{"type":55,"coordinates":56},"Point",[57,58],2.3,49.9,{"lat":58,"lon":57},[61,65],{"name":62,"role":45,"phone":63,"phoneExt":26,"email":64},"UFR STAPS","03 22 82 74 41","said.ahmaidi@u-picardie.fr",{"name":66,"role":67,"phone":26,"phoneExt":26,"email":26},"Thierry Lelard, Lecturer","PRINCIPAL_INVESTIGATOR",{"type":67,"investigatorFullName":69,"investigatorTitle":70,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Jennifer Burgos Tirado","Researcher - Ph.D student","100587528",false,"NCT06929559","Muscular Synergies and Behavioral Adaptations of Gait in Pain Anticipation (SYAMAPP)","SYAMAPP","Inclusion Criteria:\n\n* Aged 18-35 years\n* Healthy participant with no self-reported diagnosed neurological, musculoskeletal, or cardiovascular disorders\n* Body Mass Index (BMI) \\\u003C 30\n* Ability to walk unaided for at least 10 minutes without major physical limitations\n\nExclusion Criteria:\n\n* Presence of pain at the time of testing\n* Self-reported diagnosed condition affecting mobility\n* Known allergy to any component of the study cream\n* Allergy to EMG electrode adhesives\n* Inability to stand unassisted for more than 1 minute\n* Inability to walk\u002Frun at the required speed and distance\n* Weight exceeding 150 kg (due to treadmill limitations)\n* Recent intake of:\n* Analgesics (within 6 hours)\n* Cigarettes (within 6 hours)\n* Caffeine (within 2 hours)\n* Skin lesions at the cream application site\n* Pregnancy\n* Failure to understand instructions\n* Daytime pain reported by participant on day of experimentation",true,"ALL","18 Years","35 Years",{"count":82,"type":83},34,"ESTIMATED","INTERVENTIONAL",[86],"NA","The purpose of this study is to determine whether the anticipation of pain influences gait control and psychophysiological responses in healthy individuals. Participants will receive a neutral cream described either as potentially painful (experimental group) or inert (control group), and their behavioral and physiological adaptations will be measured during walking tasks.",[89,90],"Nocebo Effect","Pain Anticipation",[92,93,94,95,96,97,98,99],"Nocebo effect","Pain anticipation","Pain expectation","Motricity","Gait","Walking","Healthy","Muscle synergies","2026-06-08",{"date":102,"type":103},"2026-06-11","ACTUAL",{"date":105,"type":103},"2026-01-01",{"date":107,"type":83},"2028-10-30",{"name":5,"class":6},1]