[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100426016":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":19,"centralContacts":26,"locations":31,"responsibleParty":44,"collaborators":47,"id":50,"slug":10,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":10,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":10,"enrollmentInfo":58,"targetDuration":10,"studyType":61,"phases":10,"briefSummary":62,"conditions":63,"keywords":10,"overallStatus":34,"whyStopped":10,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Hospital San Carlos, Madrid","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"Myocardial ischemia without obstructive coronary stenosis",null,[12],"Diagnostic Test: Invasive coronary endothelium-dependent and non-endothelium-dependent physiological assessment",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"DIAGNOSTIC_TEST","Invasive coronary endothelium-dependent and non-endothelium-dependent physiological assessment","Coronary hemodynamics and vessel anatomical measures obtained during adenosine and acetylcholine evaluation with a dedicated physiology wire",[9],[20,24],{"name":21,"affiliation":22,"role":23},"Hernan Mejia-Renteria, MD, PhD","Department of Cardiology, Hospital Clinico San Carlos","PRINCIPAL_INVESTIGATOR",{"name":25,"affiliation":22,"role":23},"Javier Escaned, MD, PhD",[27],{"name":21,"role":28,"phone":29,"phoneExt":10,"email":30},"CONTACT","+34 913303283","hmejiarenteria@gmail.com",[32],{"facility":33,"status":34,"city":35,"state":10,"zip":36,"country":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":10},"Hospital Clinico San Carlos","RECRUITING","Madrid","28040","Spain",{"type":39,"coordinates":40},"Point",[41,42],-3.70256,40.4165,{"lat":42,"lon":41},{"type":23,"investigatorFullName":45,"investigatorTitle":46,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Hernan D. Mejia-Renteria","Principal Investigator",[48],{"name":49,"class":6},"Fundacion Investigacion Interhospitalaria Cardiovascular","100426016",false,"NCT04827498","Myocardial Ischemia Without Obstructive Coronary Stenoses","Myocardial Ischemia Without Obstructive Coronary Stenoses: A Prospective Observational Study With Invasive Coronary Pressure and Flow Measurements and Endothelial Function Test","Inclusion Criteria:\n\n* Written informed consent available.\n* Age ≥ 18 years.\n* Patient eligible for invasive physiological assessment with adenosine and \u002F or acetylcholine.\n\nExclusion Criteria:\n\n* Hemodynamic instability.\n* Anticipated technical issues for physiology wire measurements.\n* Culprit vessel of acute coronary syndrome\n* Contraindications for adenosine administration.\n* Contraindications for acetylcholine test.\n* Reduced life expectancy (less than 1 year).","ALL","18 Years",{"count":59,"type":60},600,"ESTIMATED","OBSERVATIONAL","Coronary-related myocardial ischemia can result from obstructive epicardial stenosis or non-obstructive causes including coronary microcirculatory dysfunction and vasomotor disorders. This prospective study has been created in order to provide knowledge in the field of non-obstructive coronary artery disease.",[64,65,66,67,68],"Myocardial Ischemia","Non-Obstructive Coronary Atherosclerosis","Microvascular Coronary Artery Disease","Vasospastic Angina","Myocardial Bridging","2021-04-23",{"date":71,"type":72},"2021-04-26","ACTUAL",{"date":74,"type":72},"2017-11-08",{"date":76,"type":60},"2030-12-31",{"name":5,"class":6},1]