[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100334814":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":16,"responsibleParty":32,"collaborators":7,"id":36,"slug":7,"hasResults":37,"nctId":38,"briefTitle":39,"officialTitle":39,"acronym":7,"eligibilityCriteria":40,"healthyVolunteers":37,"sex":41,"minAge":7,"maxAge":7,"enrollmentInfo":42,"targetDuration":45,"studyType":46,"phases":7,"briefSummary":47,"conditions":48,"keywords":7,"overallStatus":19,"whyStopped":7,"lastUpdateSubmitDate":50,"lastUpdatePostDateStruct":51,"startDateStruct":54,"completionDateStruct":56,"leadSponsor":58,"locationsCount":59},{"fullName":5,"class":6},"University of Utah","OTHER",null,[9,14],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"Josh Bonkowsky, MD, PhD","CONTACT","8012133599","joshua.bonkowsky@hsc.utah.edu",{"name":15,"role":11,"phone":12,"phoneExt":7,"email":7},"Courtney Chambers",[17],{"facility":18,"status":19,"city":20,"state":21,"zip":22,"country":23,"cosmosGeoPoint":24,"geoPoint":29,"contacts":30},"Primary Children's Hospital","RECRUITING","Salt Lake City","Utah","84113","United States",{"type":25,"coordinates":26},"Point",[27,28],-111.89105,40.76078,{"lat":28,"lon":27},[31],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},{"type":33,"investigatorFullName":34,"investigatorTitle":35,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Josh Bonkowsky","Professor, Principal Investigator","100334814",false,"NCT03639285","Natural History, Diagnosis, and Outcomes for Leukodystrophies","Inclusion Criteria:\n\n* evidence by clinical exam, radiological findings, and\u002For testing, of an inherited leukodystrophy.\n* be able to travel to the leukodystrophy clinic (at Primary Children's Hospital, Salt Lake City, Utah);\n* be able to tolerate a general physical exam, and a neurological exam.\n\nExclusion Criteria:\n\n* unable to be evaluated at the University of Utah Hospital or Primary Children's Hospital;\n* refusal to sign study consent form;\n* evidence or finding of another non-genetic cause of their condition;\n* Persons with known white matter disease or lesions related to: birth injury or prenatal injury, multiple sclerosis, trauma, infection, immunization, or post-infectious effects (e.g. ADEM- acute disseminated encephalomyelitis), metabolic disturbance (e.g. Central pontine myelinolysis), neoplasms, primary rheumatologic diseases (e.g. Systemic lupus erythematosis), stroke, hypoxic-ischemic injury, drug or toxin effect, seizures, or endocrine disturbance.","ALL",{"count":43,"type":44},600,"ESTIMATED","20 Years","OBSERVATIONAL","The goals of this protocol is to diagnose, care for, and understand the clinical histories and outcomes of people with leukodystrophies.",[49],"Leukodystrophy","2026-01-11",{"date":52,"type":53},"2026-01-13","ACTUAL",{"date":55,"type":53},"2007-01-19",{"date":57,"type":44},"2050-12-31",{"name":5,"class":6},1]