[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100533742":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":13,"locations":23,"responsibleParty":43,"collaborators":46,"id":52,"slug":7,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":53,"sex":59,"minAge":7,"maxAge":7,"enrollmentInfo":60,"targetDuration":7,"studyType":63,"phases":7,"briefSummary":64,"conditions":65,"keywords":67,"overallStatus":26,"whyStopped":7,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Centre Hospitalier Universitaire de Liege","OTHER",null,[9],{"name":10,"affiliation":11,"role":12},"Laura Vanden Brande","CHR Citadelle","PRINCIPAL_INVESTIGATOR",[14,20],{"name":15,"role":16,"phone":17,"phoneExt":18,"email":19},"Noor Benmhammed","CONTACT","43217726","+32","Noor.Benmhammed@citadelle.be",{"name":21,"role":16,"phone":7,"phoneExt":7,"email":22},"Tamara Dangouloff, PhD","tamara.dangouloff@uliege.be",[24],{"facility":25,"status":26,"city":27,"state":27,"zip":28,"country":29,"cosmosGeoPoint":30,"geoPoint":35,"contacts":36},"CHR Citadelle Liège","RECRUITING","Liège","4000","Belgium",{"type":31,"coordinates":32},"Point",[33,34],5.56749,50.63373,{"lat":34,"lon":33},[37,39,41],{"name":15,"role":16,"phone":17,"phoneExt":18,"email":38},"noor.benmhammed@citadelle.be",{"name":21,"role":16,"phone":40,"phoneExt":18,"email":22},"43215269",{"name":42,"role":12,"phone":7,"phoneExt":7,"email":7},"Laura Vanden Brande, Dr.",{"type":12,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Laurent Servais","Prof. Investigator of CRMN Liège, Principal investigator",[47,49],{"name":48,"class":6},"Centre Hospitalier Régional de la Citadelle",{"name":50,"class":51},"SYSNAV","INDUSTRY","100533742",false,"NCT06229769","Natural History Study for Patients With Angelman Syndrome","A Monocentric, Prospective, Longitudinal and Observational Natural History Study for Patients With Angelman Syndrome in CHR Citadelle Liège : NatHis-Angelman","NatHisAngelman","Inclusion Criteria:\n\n* Genetically confirmed diagnosis of AS\n* 0-99 years\n* Male or Female\n* Participant's carer is willing to give IC\u002Fsign a \"record of consultation\" for participation in the study\n\nExclusion Criteria:\n\n* comorbidity that could potentially affect the results of the study coexists. This","ALL",{"count":61,"type":62},30,"ESTIMATED","OBSERVATIONAL","This study is a 9-year natural history study for patients with Angelman syndrome in Belgium (a genetic neurodevelopmental disorder, affecting 500,000 individuals in the world). It includes a 3-year recruitment phase, a 5 year follow-up and a year to analyze the collected data. The investigators plan to include 30 patients with a semi-annual follow-up for 4 years.\n\nThe investigators will collect relevant retrospective and prospective data using age-standardized scales and questionnaires for functional motor assessments and global developmental assessment.",[66],"Angelman Syndrome",[68,69,70],"Actimyo°","Accelerometry","Daily living","2025-05-15",{"date":73,"type":74},"2025-05-20","ACTUAL",{"date":76,"type":74},"2021-10-10",{"date":78,"type":62},"2028-01",{"name":5,"class":6},1]