Natural History Study of Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation (LBSL)

ConditionsLeukoencephalopathies LBSL Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation White Matter Disease Ataxia, Cerebellar Genetic Disease

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

AgeNot listed

SponsorHugo W. Moser Research Institute at Kennedy Krieger, Inc.

About this trial

In this study, we will conduct retrospective chart and imaging reviews and prospective longitudinal virtual assessments of individuals with LBSL.

Eligibility criteria

Qualifiers

Confirmed DARS2 mutation through genetic analysis

Ability of the caregiver or participant to speak and understand English at an 8th-grade level

Disqualifiers

The vulnerable populations of prisoners, non-viable neonates, pregnant women, adults lacking the capacity to consent, non-English speakers or children who are in foster care or wards of the state.

Trial design

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Locations

Hugo Moser Center for Leukodystrophies21205, BaltimoreMaryland, United States

Sponsors and collaborators

Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

Lead sponsor

Source ClinicalTrials.gov