[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100463947":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":13,"studyPopulation":13,"armGroups":20,"interventions":27,"overallOfficials":13,"centralContacts":33,"locations":42,"responsibleParty":61,"collaborators":13,"id":65,"slug":13,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":68,"acronym":13,"eligibilityCriteria":69,"healthyVolunteers":70,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":13,"studyType":77,"phases":78,"briefSummary":79,"conditions":80,"keywords":13,"overallStatus":45,"whyStopped":13,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Peking University Cancer Hospital & Institute","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Standardized uptake value（SUV）","SUV is a semi-quantitative analysis index to describe the radioactive uptake of lesions, which has certain reference value for differentiating benign and malignant lesions。 The uptake of the tracer （68Ga-N188） in urothelial carcinoma tumor lesions by measuring SUV on PET\u002FCT.","2 years",null,{"allocation":15,"interventionModel":16,"interventionModelDescription":13,"primaryPurpose":17,"observationalModel":13,"timePerspective":13,"maskingInfo":18},"NA","SINGLE_GROUP","DIAGNOSTIC",{"masking":19,"maskingDescription":13,"whoMasked":13},"NONE",[21],{"label":22,"type":23,"description":24,"interventionNames":25},"68Ga-N188","EXPERIMENTAL","Imaging cohort All study participants will be allocated to this arm (single-arm study). Study participants will undergo 68Ga-N188 PET\u002FCT scan.",[26],"Drug: 18F-FDG",[28],{"type":29,"name":30,"description":31,"armGroupLabels":32,"otherNames":13},"DRUG","18F-FDG","All study participants will undergo one 18F-FDG PET\u002FCT scan.",[22],[34,39],{"name":35,"role":36,"phone":37,"phoneExt":13,"email":38},"Zhi Yang, Professor","CONTACT","010-88196495","pekyz@163.com",{"name":40,"role":36,"phone":37,"phoneExt":13,"email":41},"Hua Zhu, Professor","zhuhuabch@pku.edu.cn",[43],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Beijing Cancer Hospital","RECRUITING","Beijing","Beijing Municipality","100142","China","CN",{"type":52,"coordinates":53},"Point",[54,55],116.39723,39.9075,{"lat":55,"lon":54},[58],{"name":59,"role":36,"phone":13,"phoneExt":13,"email":60},"Shunlian Zhou","zhoushunlian@163.com",{"type":62,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":13,"oldOrganization":13},"PRINCIPAL_INVESTIGATOR","Hua Zhu","Professor","100463947",false,"NCT05321316","Nectin-4 Specific LMW PET Probe Imaging in Urothelial Carcinoma","Inclusion Criteria:\n\n1. 18-75 years old, male or female;\n2. Heart function is normal;\n3. Normal heart function;\n4. Estimated survival ≥12 weeks;\n5. Good follow-up compliance;\n6. presence of at least one measurable target lesion according to RECIST1.1 criteria;\n7. Women of childbearing age (15-49 years) must have a negative pregnancy test within 7 days before starting the test; Fertile men and women must agree to use effective contraception to prevent pregnancy during the study period and for 3 months after the test;\n8. Patients recommended by clinicians to undergo PET\u002FCT examination for tumor diagnostic staging;\n9. The subject patients could fully understand and voluntarily participate in the experiment, and signed the informed consent.\n\nExclusion Criteria:\n\n1. Serious abnormality of liver, kidney and blood;\n2. Pregnant patients;\n3. Pregnant and lactation women;\n\n3\\) unable to lie flat for half an hour; 4) Refuse to join the clinical investigator; 5) Suffering from claustrophobia or other mental diseases; 6) Other conditions that researchers deem unsuitable for participating in the experiment.",true,"ALL","18 Years","75 Years",{"count":75,"type":76},20,"ESTIMATED","INTERVENTIONAL",[15],"To evaluate the ability of \\[68Ga\\]N188 to detect nectin-4 overexpression in patients with urothelial carcinoma, especially in patients with recurrent or advanced bladder cancer.",[81],"Urothelial Carcinoma","2026-03-02",{"date":84,"type":85},"2026-03-04","ACTUAL",{"date":87,"type":76},"2026-05-31",{"date":89,"type":76},"2026-12",{"name":5,"class":6},1]