About this trial

This trial studies the safety and how well negative pressure wound therapy works in healing the abdominal incision in obese patients undergoing free flap breast reconstruction surgery. Using negative pressure wound therapy (NPWT) instead of standard dressing (bandages) may improve wound healing at the surgical site in the abdomen where tissue was collected for breast reconstruction surgery.

Eligibility criteria

Qualifiers

Patients undergoing a free abdominal flap, including a superficial inferior epigastric artery (SIEA), deep inferior epigastric artery perforator (DIEP), or muscle-sparing transverse rectus abdominus myocutaneous (MS-TRAM) flap for breast reconstruction.

Patients are willing and able to give consent.

Body mass index (BMI) greater than or equal to 30.0.

Disqualifiers

Patients who are unable to provide consent.

Patients who are suspected or known to be pregnant.

Known allergy to topical adhesives.

Trial design

Treatments tested in this trial

  • Negative Pressure Wound Therapy
  • Wound Care Management

Treatment groups

80 Participants
are divided into 2 treatment groups

Locations

1
M D Anderson Cancer Center77030, HoustonTexas, United States

Sponsors and collaborators

M.D. Anderson Cancer Center

Lead sponsor

National Cancer Institute (NCI)

Collaborator