[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100385235":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":23,"locations":33,"responsibleParty":49,"collaborators":10,"id":53,"slug":10,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":10,"eligibilityCriteria":57,"healthyVolunteers":54,"sex":58,"minAge":10,"maxAge":59,"enrollmentInfo":60,"targetDuration":10,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":10,"overallStatus":35,"whyStopped":10,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"Boston Children's Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group 1",null,"patients who tend to have longer CPB",[13],"Other: Research study",{"label":15,"type":10,"description":16,"interventionNames":17},"Group 2","Patients who have shorter CPB",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"Research study","Blood and tracheal aspirates will be collected",[9,15],[24,29],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Sophia Koutsogiannaki, PhD","CONTACT","617-919-4725","sophia.koutsogiannaki@childrens.harvard.edu",{"name":30,"role":26,"phone":31,"phoneExt":10,"email":32},"Koichi Yuki, MD","617-355-6225","koichi.yuki@childrens.harvard.edu",[34],{"facility":5,"status":35,"city":36,"state":37,"zip":38,"country":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"RECRUITING","Boston","Massachusetts","02115","United States",{"type":41,"coordinates":42},"Point",[43,44],-71.05977,42.35843,{"lat":44,"lon":43},[47],{"name":48,"role":26,"phone":10,"phoneExt":10,"email":10},"Rachel Bernier",{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Sophia Koutsogiannaki","Assistant Professor","100385235",false,"NCT04296071","Neutrophil Phenotypic Profiling and Acute Lung Injury in Patients After Cardiopulmonary Bypass (CPB)","Inclusion Criteria:\n\n* Are \\\u003C 12months of age\n* Scheduled for cardiac surgical needing CPB\n* Preoperative SpO2 \\> 90%\n\nExclusion Criteria:\n\n* Lack of parental (or legal guardian's) consent\n* Preoperative SpO2 \\\u003C 90%\n* Preoperative oxygen therapy","ALL","12 Months",{"count":61,"type":62},56,"ESTIMATED","OBSERVATIONAL","Acute lung injury (ALI) following cardiopulmonary bypass (CPB) is a serious complication, often prolonging the length of stay in ICU and potentially dealing to mortality. The objective of this study is to assess the mechanism of CPB-mediated acute lung injury in pediatric patients.",[66,67],"Lung Injury","Cardiopulmonary Bypass","2026-05-13",{"date":70,"type":71},"2026-05-15","ACTUAL",{"date":73,"type":71},"2022-10-14",{"date":75,"type":62},"2027-12",{"name":51,"class":6},1]