[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100598708":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":23,"centralContacts":28,"locations":10,"responsibleParty":33,"collaborators":10,"id":35,"slug":10,"hasResults":36,"nctId":37,"briefTitle":38,"officialTitle":39,"acronym":10,"eligibilityCriteria":40,"healthyVolunteers":36,"sex":41,"minAge":42,"maxAge":43,"enrollmentInfo":44,"targetDuration":10,"studyType":47,"phases":10,"briefSummary":48,"conditions":49,"keywords":10,"overallStatus":53,"whyStopped":10,"lastUpdateSubmitDate":54,"lastUpdatePostDateStruct":55,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":10},{"fullName":5,"class":6},"Saglik Bilimleri Universitesi","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Conservative",null,"Our clinic's standard anesthesia induction and maintenance method will be applied to all patients. Patients will receive standard monitoring including peripheral oxygen saturation, non-invasive blood pressure, ECG, and anesthesia depth. All patients will receive intravenous 2-2.5 mg\u002Fkg propofol under Sedline guidance, and remifentanil via target-controlled infusion at an effect-site concentration of 4 ng\u002Fml. After anesthesia depth falls below 50, 0.6 mg\u002Fkg rocuronium will be administered. Maintenance anesthesia will be with 1-2% sevoflurane in 40\u002F60% oxygen\u002Fair mixture at 2 L flow.Remifentanil is administered as a continuous infusion in conservative approach;dosage adjustments are made based on heart rate and blood pressure changes to estimate pain levels.",{"label":13,"type":10,"description":14,"interventionNames":15},"Nociceptive level","Our clinic's standard anesthesia induction and maintenance method will be applied to all patients. Patients will receive standard monitoring including peripheral oxygen saturation, non-invasive blood pressure, ECG, and anesthesia depth. All patients will receive intravenous 2-2.5 mg\u002Fkg propofol under Sedline guidance, and remifentanil via target-controlled infusion at an effect-site concentration of 4 ng\u002Fml. After anesthesia depth falls below 50, 0.6 mg\u002Fkg rocuronium will be administered. Maintenance anesthesia will be with 1-2% sevoflurane in 40\u002F60% oxygen\u002Fair mixture at 2 L flow.Remifentanil is administered as a continuous infusion by using Nociceptive level guidance",[16],"Device: nociceptive level",[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"DEVICE","nociceptive level","remifentanil infusion dose adjustment according to the changes of nociceptive level",[13],[24],{"name":25,"affiliation":26,"role":27},"Süheyla Abitağaoğlu","UNIVERSİTY OF HEALTH SCIENCES","PRINCIPAL_INVESTIGATOR",[29],{"name":25,"role":30,"phone":31,"phoneExt":10,"email":32},"CONTACT","05325267656","suheylaatay81@gmail.com",{"type":27,"investigatorFullName":25,"investigatorTitle":34,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Associate Professor, MD","100598708",false,"NCT07075003","NOL-Guided vs Conventional Intraoperative Opioid Infusion on Outcomes in Geriatric Patients","Effect of NOL-Guided vs Conventional Intraoperative Opioid Infusion on Outcomes in Geriatric Patients Undergoing Lumbar Stabilization Surgery","Inclusion Criteria:\n\n* Patients undergoing lumbar stabilization surgery\n\nExclusion Criteria:\n\n* Chronic opioid use\n* Severe congestive heart failıure\n* Severe arrhythmia\n* Uncontrolled hypertension","ALL","65 Years","90 Years",{"count":45,"type":46},80,"ESTIMATED","OBSERVATIONAL","The aim of this study is to compare the effects of conventional methods and goal-directed therapy guided by pain monitoring on total remifentanil dosage, wake-up time, and complications in geriatric patients undergoing lumbar stabilization surgery.",[50,51,52],"Pain","Opioid Use","Geriatric Anesthesia","NOT_YET_RECRUITING","2025-07-10",{"date":56,"type":57},"2025-07-20","ACTUAL",{"date":59,"type":46},"2025-07",{"date":61,"type":46},"2025-10",{"name":5,"class":6}]