[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100338258":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":22,"centralContacts":26,"locations":33,"responsibleParty":49,"collaborators":31,"id":51,"slug":31,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":31,"eligibilityCriteria":56,"healthyVolunteers":52,"sex":57,"minAge":58,"maxAge":31,"enrollmentInfo":59,"targetDuration":31,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":72,"overallStatus":35,"whyStopped":31,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"University of Miami","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"IDH-Mutant Glioma Patients","EXPERIMENTAL","Patients who have suspected or confirmed gliomas and are scheduled to undergo biopsy or resection of their brain tumors will receive a 3 Tesla (3T) Magnetic Resonance Imaging (MRI) scan of their brain.",[13],"Device: 3T MRI Scanner",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DEVICE","3T MRI Scanner","3T MRI Scanner providing Mega-laser sequence for single-voxel Magnetic Resonance Spectroscopy (MRS) data for 2 hydroxyglutarate (2HG) quantitation.",[9],[21],"3 Tesla (3T) Magnetic Resonance Imaging Scanner",[23],{"name":24,"affiliation":5,"role":25},"Macarena De La Fuente, MD","PRINCIPAL_INVESTIGATOR",[27],{"name":28,"role":29,"phone":30,"phoneExt":31,"email":32},"Nathalie Padron","CONTACT","305-243-3530",null,"npadron@med.miami.edu",[34],{"facility":5,"status":35,"city":36,"state":37,"zip":38,"country":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"RECRUITING","Miami","Florida","33136","United States",{"type":41,"coordinates":42},"Point",[43,44],-80.19366,25.77427,{"lat":44,"lon":43},[47,48],{"name":28,"role":29,"phone":30,"phoneExt":31,"email":32},{"name":24,"role":25,"phone":31,"phoneExt":31,"email":31},{"type":25,"investigatorFullName":24,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"Assistance Professor","100338258",false,"NCT03684109","Non-invasive Glioma Characterization Through Molecular Imaging","Pilot Study for Non-invasive Glioma Characterization Through Molecular Imaging","Inclusion Criteria:\n\n* Adults (≥18 year old)\n* Subjects with suspected or confirmed gliomas and who will have a medically indicated biopsy or resection of his\u002Fher brain lesion.\n\nExclusion Criteria:\n\n* Adults unable to consent\n* Individuals who are not yet adults (infants, children, teenagers)\n* Pregnant women\n* Patients unable to have MRI done","ALL","18 Years",{"count":60,"type":61},30,"ESTIMATED","INTERVENTIONAL",[64],"NA","MRI-based sequences can provide non-invasive quantification of intratumoral 2-hydroxyglutarate (2HG) distribution and tumor cellularity in human gliomas and help guide the development of novel glioma therapies.",[67,68,69,70,71],"Glioma","Brain Tumor","Primary Brain Tumor","Malignant Glioma","Malignant Primary Brain Tumor",[73,74,75,76],"Non-invasive glioma characterization","Molecular Imaging","Isocitrate Dehydrogenase (IDH) Mutations","MRI-Based Sequencing","2026-04-14",{"date":79,"type":80},"2026-04-20","ACTUAL",{"date":82,"type":80},"2019-01-25",{"date":84,"type":61},"2027-01-31",{"name":5,"class":6},1]