[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100597906":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":32,"locations":37,"responsibleParty":54,"collaborators":11,"id":57,"slug":11,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":60,"acronym":11,"eligibilityCriteria":61,"healthyVolunteers":58,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":11,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":11,"overallStatus":40,"whyStopped":11,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"West China Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"ROS-scavenging Nanoenzymes","EXPERIMENTAL",null,[13],"Drug: ROS-scavenging Nanoenzymes",{"label":15,"type":16,"description":11,"interventionNames":17},"Standard of care","ACTIVE_COMPARATOR",[18],"Behavioral: Standard of care",[20,24],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":11},"DRUG","ROS-scavenging nanoenzymes are applied to the treatment area, once daily during radiotherapy.",[9],{"type":25,"name":15,"description":15,"armGroupLabels":26,"otherNames":11},"BEHAVIORAL",[15],[28],{"name":29,"affiliation":30,"role":31},"Xingchen Peng, Prof.","Sichuan University West China Hospital","PRINCIPAL_INVESTIGATOR",[33],{"name":29,"role":34,"phone":35,"phoneExt":11,"email":36},"CONTACT","+86 18980606753","pxx2014@163.com",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"West China Hospital, Sichuan University","RECRUITING","Chengdu","Sichuan","610000","China",{"type":46,"coordinates":47},"Point",[48,49],104.06667,30.66667,{"lat":49,"lon":48},[52],{"name":53,"role":34,"phone":11,"phoneExt":11,"email":11},"Xingchen Peng, Phd, MD",{"type":31,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Xingchen Peng","Professor","100597906",false,"NCT07064577","Novel ROS-scavenging Nanoenzymes for the Treatment of Radiation Dermatitis in Patients With Head and Neck Cancer","Inclusion Criteria:\n\n1. Patients with a pathological diagnosis of non-metastatic head and neck malignant tumors;\n2. Patients deemed suitable for high-dose radiotherapy, either as a primary treatment or as postoperative treatment following surgical resection.\n\nExclusion Criteria:\n\n1. Eastern Cooperative Oncology Group performance status of \\>2;\n2. Pre-existing skin rash, ulceration or open wound in the treatment area;\n3. Inflammatory or connective tissue disorder of the skin;\n4. History of head and neck radiotherapy.","ALL","18 Years","80 Years",{"count":66,"type":67},30,"ESTIMATED","INTERVENTIONAL",[70],"NA","There is no standard treatment for radiation dermatitis. In this study, the investigators have designed novel ROS-scavenging nanoenzymes and aim to evaluate their effectiveness in preventing radiation dermatitis in patients with head and neck cancer.",[73],"Radiation Dermatitis","2025-08-03",{"date":76,"type":77},"2025-08-07","ACTUAL",{"date":79,"type":77},"2025-07-15",{"date":81,"type":67},"2025-10-15",{"name":5,"class":6},1]