[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100556926":3},{"organization":4,"outcomesModule":7,"designInfo":31,"detailedDescription":30,"studyPopulation":30,"armGroups":43,"interventions":66,"overallOfficials":84,"centralContacts":89,"locations":98,"responsibleParty":116,"collaborators":30,"id":119,"slug":30,"hasResults":120,"nctId":121,"briefTitle":122,"officialTitle":123,"acronym":30,"eligibilityCriteria":124,"healthyVolunteers":120,"sex":125,"minAge":126,"maxAge":30,"enrollmentInfo":127,"targetDuration":30,"studyType":130,"phases":131,"briefSummary":133,"conditions":134,"keywords":137,"overallStatus":101,"whyStopped":30,"lastUpdateSubmitDate":144,"lastUpdatePostDateStruct":145,"startDateStruct":148,"completionDateStruct":150,"leadSponsor":152,"locationsCount":153},{"fullName":5,"class":6},"National Institute of Respiratory Diseases, Mexico","OTHER_GOV",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":30},[9],{"measure":10,"description":11,"timeFrame":12},"30-day incidence infection","Incidence of infectious complications after surgery diagnosed using any of these criteria:\n\nInfection of surgery wound confirmed by culture Infection confirmed by blood culture Pneumonia developed after surgery confirmed by chest x Ray.","30-day incidence infection following lung resection in lung cancer patients.",[14,18,20,22,26],{"measure":15,"description":16,"timeFrame":17},"Changes in prostaglandin E2","Measured in serum sample made by Enzyme-linked immunosorbent assay (ELISA).","At the beginning of nutritional therapy and at day-4 following surgery",{"measure":19,"description":16,"timeFrame":17},"Changes in Interleukin-6",{"measure":21,"description":16,"timeFrame":17},"Changes in Tumor Necrosis Factor Alpha (TNF-α)",{"measure":23,"description":24,"timeFrame":25},"Number of participants with therapeutic antibiotics prescription","Frequency of therapeutic antibiotics prescription will be collected from medical records and medication administration registers.","During the hospital stay until 30-day",{"measure":27,"description":28,"timeFrame":29},"Hospital lenght of stay","Number of calendar days that elapsed since hospital admission to the day of hospital discharge","During the hospital stay until 90-day",null,{"allocation":32,"interventionModel":33,"interventionModelDescription":34,"primaryPurpose":35,"observationalModel":30,"timePerspective":30,"maskingInfo":36},"RANDOMIZED","PARALLEL","Randomized Clinical Trial","PREVENTION",{"masking":37,"maskingDescription":38,"whoMasked":39},"TRIPLE","Use of enteral formula enriched with omega-3 or standard not revealed for participants.",[40,41,42],"PARTICIPANT","CARE_PROVIDER","OUTCOMES_ASSESSOR",[44,50,55,61],{"label":45,"type":46,"description":47,"interventionNames":48},"Experimental enteral nutrition","EXPERIMENTAL","Patients admitted to the hospital at least three days before surgery Use of an enteral feeding tube to administer enriched enteral formula",[49],"Dietary Supplement: Fish oil enteral supplementation",{"label":51,"type":46,"description":52,"interventionNames":53},"Experimental oral nutrition","Patients admitted one day before surgery. Home-self administration of enriched enteral formula three days before surgery",[54],"Dietary Supplement: Fish oil oral supplementation",{"label":56,"type":57,"description":58,"interventionNames":59},"Standard enteral nutrition","OTHER","Patients admitted to the hospital at least three days before surgery Use of an enteral feeding tube to administer standard enteral formula",[60],"Dietary Supplement: Enteral nutrition without fish oil",{"label":62,"type":57,"description":63,"interventionNames":64},"Standard oral nutrition","Patients admitted one day before surgery. Home-self administration of standard enteral formula three days before surgery",[65],"Dietary Supplement: Oral nutritional supplement without fish oil",[67,72,76,80],{"type":68,"name":69,"description":70,"armGroupLabels":71,"otherNames":30},"DIETARY_SUPPLEMENT","Fish oil enteral supplementation","Omega-3 (4.2 g), administered through an enteral feeding tube, three days before surgery",[45],{"type":68,"name":73,"description":74,"armGroupLabels":75,"otherNames":30},"Fish oil oral supplementation","Omega-3 (4.2 g), orally administered enriched nutritional formula, drinking at home three days before surgery",[51],{"type":68,"name":77,"description":78,"armGroupLabels":79,"otherNames":30},"Enteral nutrition without fish oil","Enteral formula without omega-3 administered through an enteral feeding tube, three days before surgery",[56],{"type":68,"name":81,"description":82,"armGroupLabels":83,"otherNames":30},"Oral nutritional supplement without fish oil","Oral nutritional supplement without omega-3 orally administered, drinking at home three days before surgery",[62],[85],{"name":86,"affiliation":87,"role":88},"Ivan A Osuna-Padilla, PhD","Instituto Nacional de Enfermedades Respiratorias","PRINCIPAL_INVESTIGATOR",[90,95],{"name":86,"role":91,"phone":92,"phoneExt":93,"email":94},"CONTACT","5487-1700","5059","ivan.osuna@iner.gob.mx",{"name":96,"role":91,"phone":92,"phoneExt":93,"email":97},"Ana L Gómez-Rodriguez, MSc","grolucia@yahoo.es",[99],{"facility":100,"status":101,"city":102,"state":30,"zip":103,"country":104,"countryCode":105,"cosmosGeoPoint":106,"geoPoint":111,"contacts":112},"National Institute of Respiratory Diseases","RECRUITING","Mexico City","14080","Mexico","MX",{"type":107,"coordinates":108},"Point",[109,110],-99.12766,19.42847,{"lat":110,"lon":109},[113],{"name":114,"role":91,"phone":115,"phoneExt":30,"email":97},"Ana L Gomez-Rodriguez, MSc","+52 1 55 2573 2734",{"type":88,"investigatorFullName":117,"investigatorTitle":118,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"Ivan Armando Osuna Padilla","Clinical Nutrition Manager","100556926",false,"NCT06531460","Nutritional Therapy Enriched With Omega-3 in Patients With Lung Resection","Effect of Perioperative Nutrition Enriched With Omega-3 on the Incidence of Infections in Oncologic Patients Following Lung Resection","Inclusion Criteria:\n\n* Lung cancer diagnosis\n* Elective surgery for lung resection schedule at least four days before surgery\n* Signed informed consent.\n\nExclusion Criteria:\n\n* Acute or chronic organ failure as hepatic or renal insufficiency\n* Patients with fish-allergy\n* History of any surgery within 3 months\n* Immunocompromised patients","ALL","18 Years",{"count":128,"type":129},310,"ESTIMATED","INTERVENTIONAL",[132],"NA","The aim of this study is to analyze the effect of enriched formula with omega-3 in the 30-day incidence infection and inflammatory response following lung resection surgery in lung cancer patients.",[135,136],"Lung Cancer","Surgery",[138,139,140,141,142,143],"lung cancer","omega-3","prehabilitation nutrition","perioperative nutrition","infections","inflammation response","2024-07-29",{"date":146,"type":147},"2024-08-01","ACTUAL",{"date":149,"type":147},"2024-07-25",{"date":151,"type":129},"2027-07",{"name":5,"class":6},1]