[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100499498":3},{"organization":4,"outcomesModule":7,"designInfo":29,"detailedDescription":28,"studyPopulation":32,"armGroups":33,"interventions":40,"overallOfficials":49,"centralContacts":54,"locations":63,"responsibleParty":101,"collaborators":103,"id":107,"slug":28,"hasResults":108,"nctId":109,"briefTitle":110,"officialTitle":111,"acronym":28,"eligibilityCriteria":112,"healthyVolunteers":108,"sex":113,"minAge":114,"maxAge":28,"enrollmentInfo":115,"targetDuration":118,"studyType":119,"phases":28,"briefSummary":120,"conditions":121,"keywords":28,"overallStatus":66,"whyStopped":28,"lastUpdateSubmitDate":124,"lastUpdatePostDateStruct":125,"startDateStruct":128,"completionDateStruct":129,"leadSponsor":131,"locationsCount":132},{"fullName":5,"class":6},"Hospital Israelita Albert Einstein","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":28},[9],{"measure":10,"description":11,"timeFrame":12},"Composed of incidence of rash, fever, adenopathy, general pain, chills, weakness, occurrence of hospitalization, and neurological repercussions","symptoms' incidence in participants with mpox infection","Up to 90 days after the inclusion",[14,17,21,24],{"measure":15,"description":16,"timeFrame":12},"Death","Incidence of death",{"measure":18,"description":19,"timeFrame":20},"Hospitalizations","Incidence of hospitalization","Days 15, 30, 60, and 90",{"measure":22,"description":23,"timeFrame":20},"Untargeted metabolomics of total plasmas and skin lesion","Changes among visits of Immune-metabolomics responses related to symptoms' incidence",{"measure":25,"description":26,"timeFrame":27},"Viral genomic","Evaluation of the pattern of viral genome of the mpox virus circulation in Brazil","Day 0",null,{"allocation":28,"interventionModel":28,"interventionModelDescription":28,"primaryPurpose":28,"observationalModel":30,"timePerspective":31,"maskingInfo":28},"COHORT","PROSPECTIVE","Individuals who have risk factors for mpox infection in Brazil.",[34],{"label":35,"type":28,"description":36,"interventionNames":37},"Human cases of monkeypox confirmed by PCR","Laboratory-confirmed mpox infection is defined as determined by polymerase chain reaction assay (PCR), culture, or antigen test obtained from a sample collected from blood, oropharynx, anal or skin lesion within 5 days of inclusion.",[38,39],"Diagnostic Test: Viral genomic","Diagnostic Test: Untargeted Metabolomics",[41,45],{"type":42,"name":25,"description":43,"armGroupLabels":44,"otherNames":28},"DIAGNOSTIC_TEST","Evaluation of mpox viral genomic",[35],{"type":42,"name":46,"description":47,"armGroupLabels":48,"otherNames":28},"Untargeted Metabolomics","Evaluation of metabolomics of the total plasma, oropharynx, and skin samples.",[35],[50],{"name":51,"affiliation":52,"role":53},"Henrique Fonseca","Hospital Albert Einstein","STUDY_CHAIR",[55,60],{"name":56,"role":57,"phone":58,"phoneExt":28,"email":59},"Henrique AR Fonseca, PhD","CONTACT","+5511968308958","henrique.fonseca@einstein.br",{"name":61,"role":57,"phone":28,"phoneExt":28,"email":62},"Diogo Moia, PharmD","diogo.moia@einstein.br",[64,80,90],{"facility":65,"status":66,"city":67,"state":68,"zip":28,"country":69,"countryCode":70,"cosmosGeoPoint":71,"geoPoint":76,"contacts":77},"Hospital Universitário João de Barros Barreto","RECRUITING","Belém","Pará","Brazil","BR",{"type":72,"coordinates":73},"Point",[74,75],-48.50444,-1.45583,{"lat":75,"lon":74},[78],{"name":79,"role":57,"phone":28,"phoneExt":28,"email":28},"Rita Sousa, MD-PhD",{"facility":5,"status":66,"city":81,"state":81,"zip":28,"country":69,"countryCode":70,"cosmosGeoPoint":82,"geoPoint":86,"contacts":87},"São Paulo",{"type":72,"coordinates":83},[84,85],-46.63611,-23.5475,{"lat":85,"lon":84},[88],{"name":89,"role":57,"phone":28,"phoneExt":28,"email":28},"Lucas Theotônio, MD-PhD",{"facility":91,"status":66,"city":92,"state":28,"zip":28,"country":69,"countryCode":70,"cosmosGeoPoint":93,"geoPoint":97,"contacts":98},"Hospital Naval Marcílio Dias","Rio de Janeiro",{"type":72,"coordinates":94},[95,96],-43.18223,-22.90642,{"lat":96,"lon":95},[99],{"name":100,"role":57,"phone":28,"phoneExt":28,"email":28},"Hemerson Luz, MD-PhD",{"type":102,"investigatorFullName":28,"investigatorTitle":28,"investigatorAffiliation":28,"oldNameTitle":28,"oldOrganization":28},"SPONSOR",[104],{"name":105,"class":106},"Ministry of Health, Brazil","OTHER_GOV","100499498",false,"NCT05784038","Observational, Prospective, Cohort Study of Mpox Infection in Brazil (NETPOX)","Observational, Prospective, Cohort Study of Mpox Infection in Brazil - NETPOX Cohort","Inclusion Criteria:\n\n* Men and women aged ≥ 18 years with confirmed MPOX infection.\n\n(laboratory-confirmed monkeypox infection is defined as determined by PCR, culture, or antigen test obtained from a sample collected from blood, oropharynx, anal or skin lesion within 4 days of randomization)\n\nExclusion Criteria:\n\n* Inability to provide informed consent;\n* Patient who, judging by the study team, does not have a condition for decentralized follow-up","ALL","18 Years",{"count":116,"type":117},80,"ESTIMATED","10 Months","OBSERVATIONAL","The study is a prospective cohort that evaluates the clinical and immune-metabolic variables that may be linked to the risk and severity of the infection or even hospitalization or death in patients infected with the Mpox virus in Brazil. The expectation is to include at least 80 patients over six months, with a follow-up of 90 days from inclusion, through contact via decentralized visits.",[122,123],"Monkeypox","MPOX","2024-07-16",{"date":126,"type":127},"2024-07-17","ACTUAL",{"date":124,"type":127},{"date":130,"type":117},"2026-12",{"name":5,"class":6},3]