[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633701":3},{"organization":4,"outcomesModule":7,"designInfo":23,"detailedDescription":22,"studyPopulation":26,"armGroups":22,"interventions":22,"overallOfficials":22,"centralContacts":27,"locations":22,"responsibleParty":33,"collaborators":22,"id":37,"slug":22,"hasResults":38,"nctId":39,"briefTitle":40,"officialTitle":41,"acronym":22,"eligibilityCriteria":42,"healthyVolunteers":38,"sex":43,"minAge":44,"maxAge":22,"enrollmentInfo":45,"targetDuration":22,"studyType":48,"phases":22,"briefSummary":49,"conditions":50,"keywords":22,"overallStatus":52,"whyStopped":22,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":54,"startDateStruct":57,"completionDateStruct":59,"leadSponsor":61,"locationsCount":22},{"fullName":5,"class":6},"IRCCS Ospedale San Raffaele","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":17,"otherOutcomes":22},[9,13,15],{"measure":10,"description":11,"timeFrame":12},"Major clinical adverse outcomes","Cardiovascular mortality","1 year and 5 years follow up",{"measure":10,"description":14,"timeFrame":12},"cardiovascular rehospitalization",{"measure":10,"description":16,"timeFrame":12},"all-cause mortality",[18],{"measure":19,"description":20,"timeFrame":21},"need of re-implantation of CIED for patients who underwent TLE","Eventual re-implantation after TLE, during the sane or a following hospitalization.\n\nTiming between TLE and re-implantation","discharge, 1 and 5 years",null,{"allocation":22,"interventionModel":22,"interventionModelDescription":22,"primaryPurpose":22,"observationalModel":24,"timePerspective":25,"maskingInfo":22},"CASE_ONLY","RETROSPECTIVE","patients underwent TLE for lead and pocket infection",[28],{"name":29,"role":30,"phone":31,"phoneExt":22,"email":32},"SImone Gulletta, MD","CONTACT","02 2643 7484","gulletta.simone@hsr.it",{"type":34,"investigatorFullName":35,"investigatorTitle":36,"investigatorAffiliation":5,"oldNameTitle":22,"oldOrganization":22},"PRINCIPAL_INVESTIGATOR","Simone Gulletta","Principal investigator","100633701",false,"NCT07530107","Observational, Retrospective, Single-center Study Aimed at Evaluating Long-term Outcomes Following Transvenous Lead Extraction of Infected Cardiac Implantable Electronic Devices.","Long Term Outcomes of Cardiac Implantable Electronic Device Infections and Transvenous Lead Extraction: a Single Center Retrospective","Inclusion Criteria:\n\n* Patients ≥ 18 years.\n* Patients who underwent explantation of a single-chamber, dual-chamber, or biventricular pacemaker, or an intracardiac defibrillator, due to pocket infection, lead-related infection, or endocarditis at San Raffaele Hospital between January 2004 and November 2020.\n\nExclusion Criteria:\n\n* Lack of active status of follow-up","ALL","18 Years",{"count":46,"type":47},300,"ESTIMATED","OBSERVATIONAL","The study aims to review the centre experience in previous 20 years to understand clinical course of patients underwent TLE for lead and pocket infection, to better understand prognosis, re-implant indication, timing and strategy, and long term outcomes.",[51],"Cardiac Implantable Electronic Device (CIED)","NOT_YET_RECRUITING","2026-04-08",{"date":55,"type":56},"2026-04-15","ACTUAL",{"date":58,"type":47},"2026-05-01",{"date":60,"type":47},"2027-01-01",{"name":5,"class":6}]