[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100488661":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":13,"studyPopulation":17,"armGroups":18,"interventions":24,"overallOfficials":13,"centralContacts":29,"locations":35,"responsibleParty":58,"collaborators":13,"id":60,"slug":13,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":13,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":68,"maxAge":13,"enrollmentInfo":69,"targetDuration":13,"studyType":72,"phases":13,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":38,"whyStopped":13,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Masonic Cancer Center, University of Minnesota","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Studying biomarker levels in firefighters pre and post fire call.","The investigators will evaluate the differences between mean pre-exposure biomarker levels and post-exposure levels in urine and buccal samples collected within 24 hours post-exposure and 1-week post-exposure respectively using t-tests to test for statistical significance.","48 months",null,{"allocation":13,"interventionModel":13,"interventionModelDescription":13,"primaryPurpose":13,"observationalModel":15,"timePerspective":16,"maskingInfo":13},"CASE_ONLY","PROSPECTIVE","Firefighters who are exposed to fires containing carcinogens will join this study. Three sample collections will be taken to measure the biomarkers; pre-exposure, 24h post-exposure and 1 week post-exposure.",[19],{"label":20,"type":13,"description":21,"interventionNames":22},"Firefighters over 18 years old","This is a within subject, observational study of firefighters. This study will involve three sample collections including buccal cells and urine samples; one collection pre and two collections post-structural fire exposure.",[23],"Other: Sample collection",[25],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":13},"Sample collection","This study will involve three sample collections including buccal cells and urine samples",[20],[30],{"name":31,"role":32,"phone":33,"phoneExt":13,"email":34},"Joni Jensen","CONTACT","612-624-5178","jense010@umn.edu",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Masonic Cancer Center","RECRUITING","Minneapolis","Minnesota","55455","United States","US",{"type":45,"coordinates":46},"Point",[47,48],-93.26384,44.97997,{"lat":48,"lon":47},[51,55],{"name":52,"role":32,"phone":53,"phoneExt":13,"email":54},"Stephen S Hecht","612-624-7604","hetcht002@umn.edu",{"name":56,"role":32,"phone":57,"phoneExt":13,"email":34},"Joni A Jensen","+1 612-624-7604",{"type":59,"investigatorFullName":13,"investigatorTitle":13,"investigatorAffiliation":13,"oldNameTitle":13,"oldOrganization":13},"SPONSOR","100488661",false,"NCT05643014","Observational Study of Exposure to Environmental Toxicants Among Firefighters","Evaluate the Exposure to Toxicants Emitted During a Structural Fire Assessed by Urinary and Buccal Cell Biomarkers Found in Firefighters.","Inclusion Criteria:\n\n* Firefighter (career or volunteer)\n* Over 18 years of age\n* Able to provide written voluntary consent\n\nExclusion Criteria:\n\n* Unwilling to provide a pre and post-exposure urine sample\n* Current cancer diagnosis\n* Tobacco use within the last 1 year (verified by urinary TNEs)",true,"ALL","18 Years",{"count":70,"type":71},60,"ESTIMATED","OBSERVATIONAL","Observational, within subject study design with 1 pre and 2 post-fire exposure biomarker samples collected to assess exposure to toxicants from combustion emissions related to fighting a structural fire.",[75],"Healthy",[77,78,79,80],"PAH","1-HOP","PheT","SPMA","2026-03-10",{"date":83,"type":84},"2026-03-12","ACTUAL",{"date":86,"type":84},"2020-02-01",{"date":88,"type":71},"2027-12-31",{"name":5,"class":6},1]