[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100497633":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":33,"centralContacts":37,"locations":46,"responsibleParty":65,"collaborators":68,"id":71,"slug":32,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":32,"eligibilityCriteria":76,"healthyVolunteers":77,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":32,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":92,"overallStatus":48,"whyStopped":32,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"Massachusetts General Hospital","OTHER",[8,14,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"Healthy cornea","EXPERIMENTAL","Optical imaging of the cornea in healthy subjects",[13],"Device: Optical imaging of the tissues",{"label":15,"type":10,"description":16,"interventionNames":17},"Healthy skin","Optical imaging of the skin in healthy subjects",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Healthy gingiva","Optical imaging of the gingiva in healthy subjects",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"Keratoconus cornea","Optical imaging of the cornea in mild and moderate keratoconus",[13],[27],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"DEVICE","Optical imaging of the tissues","OCT vibrography",[9,19,15,23],null,[34],{"name":35,"affiliation":5,"role":36},"Seok-Hyun Yun, PhD","PRINCIPAL_INVESTIGATOR",[38,43],{"name":39,"role":40,"phone":41,"phoneExt":32,"email":42},"Jing Zhang, PhD","CONTACT","6173730127","jzhang110@mgh.harvard.edu",{"name":35,"role":40,"phone":44,"phoneExt":32,"email":45},"6177688704","syun@mgh.harvard.edu",[47],{"facility":5,"status":48,"city":49,"state":50,"zip":51,"country":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"RECRUITING","Boston","Massachusetts","02114","United States",{"type":54,"coordinates":55},"Point",[56,57],-71.05977,42.35843,{"lat":57,"lon":56},[60,62,63],{"name":39,"role":40,"phone":61,"phoneExt":32,"email":42},"617-373-0127",{"name":35,"role":40,"phone":44,"phoneExt":32,"email":45},{"name":35,"role":64,"phone":32,"phoneExt":32,"email":32},"SUB_INVESTIGATOR",{"type":36,"investigatorFullName":66,"investigatorTitle":67,"investigatorAffiliation":5,"oldNameTitle":32,"oldOrganization":32},"Seok Hyun Yun","Professor of Dermatology",[69],{"name":70,"class":6},"Massachusetts Eye and Ear Infirmary","100497633",false,"NCT05759780","OCT Vibrography for Biomechanical Properties of Tissues","A Study to Test the Potential of OCT Vibrography for Measuring Biomechanical Properties of Tissues","Group 1:\n\nInclusion criteria:\n\n• Subjects with healthy eyes (age 18 - 75, N = 50)\n\nExclusion criteria:\n\n* Subjects with history of eye diseases, and previous eye surgeries.\n* Subjects with diabetes, glaucoma family history\n* Subjects allergic to anesthetic eyedrop, especially proparacaine\n* Subjects with severe allergy\n* Subjects who have difficulty biting\n* Subjects who have recurrent corneal erosion\n\nGroup 2:\n\nInclusion criteria:\n\n• Subjects with healthy skin (age 18 - 75, N = 10)\n\nExclusion criteria:\n\n• Subjects with open cuts\u002Fsores on the skin, skin infection, or any contagious skin condition\n\nGroup 3:\n\nInclusion criteria:\n\n• Subjects with healthy gingiva (age 18 - 75, N = 10)\n\nExclusion criteria:\n\n• Subjects with open cuts\u002Fsores on the gingiva, gingiva infection, or any contagious gingiva condition\n\nGroup 4:\n\nInclusion criteria:\n\n• Mild or moderate keratoconus subjects (age 18 - 40, N = 20)\n\nExclusion criteria:\n\n• Subjects with K-max above 60 diopters (Pentacam imaging) are excluded",true,"ALL","18 Years","75 Years",{"count":82,"type":83},90,"ESTIMATED","INTERVENTIONAL",[86],"NA","The overall goal of this study is to develop OCT Vibrography (aka OCT elastography) as a novel tool for measuring biomechanical properties of human tissues in vivo.",[89,90,91],"Cornea","Skin Diseases","Gingival Diseases",[93,94,95,96,97,98],"biomechanics","cornea","skin","gingiva","optical coherence tomography","vibrography","2025-10-21",{"date":101,"type":102},"2025-10-23","ACTUAL",{"date":104,"type":102},"2023-08-19",{"date":106,"type":83},"2026-08-28",{"name":5,"class":6},1]