[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100413390":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":20,"studyPopulation":13,"armGroups":21,"interventions":28,"overallOfficials":33,"centralContacts":37,"locations":46,"responsibleParty":64,"collaborators":13,"id":66,"slug":13,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":67,"sex":73,"minAge":74,"maxAge":13,"enrollmentInfo":75,"targetDuration":13,"studyType":78,"phases":79,"briefSummary":80,"conditions":81,"keywords":13,"overallStatus":48,"whyStopped":13,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Medical University Innsbruck","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Optimal (shortest) activation time of the right and left ventricular in heart failure patients after CRT implantation","The activation time will be measured in 16 different device programming settings","The measurements will be done at Day 1",null,{"allocation":15,"interventionModel":16,"interventionModelDescription":13,"primaryPurpose":17,"observationalModel":13,"timePerspective":13,"maskingInfo":18},"NA","SINGLE_GROUP","DIAGNOSTIC",{"masking":19,"maskingDescription":13,"whoMasked":13},"NONE","Patient specific anatomic parameters taken from the cardiac magnetic resonance examination will be the base for a semiautomatic model incorporating the conductivity of the heart, the lungs, blood and the torso. For this reason, a software package (AMIRA Developer, TGS Template Graphics Software, France) has been adapted to calculate a quasi static approximation of Maxwell equations.\n\nAfter fusion of the T1 CMR scan and the ECG electrodes a model-based bidomain FEM is used for a step-wise measurement of the local activation times (resting potential: 290 mV; plateau: 0 mV; acceleration time: 3 ms) both Ende- and epicardially.",[22],{"label":23,"type":24,"description":25,"interventionNames":26},"Device programming","EXPERIMENTAL","according to different settings from the SyncAV algorithm",[27],"Device: Device programming",[29],{"type":30,"name":23,"description":31,"armGroupLabels":32,"otherNames":13},"DEVICE","Non-invasive electrophysiology with 65 ECG leads will be performed in 16 different device programming",[23],[34],{"name":35,"affiliation":5,"role":36},"Wolfgang Dichtl, MD PhD","PRINCIPAL_INVESTIGATOR",[38,42],{"name":35,"role":39,"phone":40,"phoneExt":13,"email":41},"CONTACT","004351250481388","dichtl@me.com",{"name":43,"role":39,"phone":44,"phoneExt":13,"email":45},"Fabian Barbieri, MD","004351250482546","fabian.barbieri@i-med.ac.at",[47],{"facility":5,"status":48,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"RECRUITING","Innsbruck","Tyrol","6020","Austria","AT",{"type":55,"coordinates":56},"Point",[57,58],11.39454,47.26266,{"lat":58,"lon":57},[61,62],{"name":35,"role":39,"phone":40,"phoneExt":13,"email":41},{"name":43,"role":39,"phone":63,"phoneExt":13,"email":45},"00435125048546",{"type":65,"investigatorFullName":13,"investigatorTitle":13,"investigatorAffiliation":13,"oldNameTitle":13,"oldOrganization":13},"SPONSOR","100413390",false,"NCT04662970","Optimization of Cardiac Resynchronization Therapy by Non-Invasive Imaging of Cardiac Electrophysiology","Optimization of Cardiac Resynchronization Therapy by Non-Invasive Imaging of Cardiac Electrophysiology: A Pilot Study","NICE CRT","Inclusion Criteria:\n\n* patients after successful implantation of a CRT-D or CRT-P device in whom a cardiac magnetic resonance examination is possible and the device is equipped with the SyncAV® programming software\n* left bundle branch block before CRT implantation\n* PQ interval ≤ 250 ms before implantation\n\nExclusion Criteria:\n\n* high-grade AV block\n* any contraindication concerning a safe CMR performance including claustrophobia\n* terminal heart failure (NYHA IV) or cardiac decompensation\n* life expectancy \\\u003C 1 year\n* women with child-bearing potential, pregnancy\n* drug abusus","ALL","18 Years",{"count":76,"type":77},25,"ESTIMATED","INTERVENTIONAL",[15],"The principal aim is to analyze total left and right ventricular activation time in different CRT device programming algorithms (SyncAV) measured by non-invasive electrophysiology",[82],"Heart Failure","2025-09-29",{"date":85,"type":86},"2025-10-02","ACTUAL",{"date":88,"type":86},"2020-01-01",{"date":90,"type":77},"2027-12-31",{"name":5,"class":6},1]