[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100541894":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":33,"centralContacts":37,"locations":47,"responsibleParty":64,"collaborators":42,"id":66,"slug":42,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":42,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":73,"maxAge":42,"enrollmentInfo":74,"targetDuration":42,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":49,"whyStopped":42,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Wake Forest University Health Sciences","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"SENNA","EXPERIMENTAL","Group A participants will be prescribed oral senna (Senokot; Atlantis Consumer Healthcare Inc., Bridgewater, NJ) 8.6mg tablets and be instructed to start with two tablets on the morning of Post Operative Day (POD)#1. Participant will continue taking two tablets on the daily. If no bowel movement on the morning of POD#3 participant may take 2 tablets in the morning and another 2 tablets that evening. The same can be replicated on POD#4. If no bowel movement on the morning of POD#5 participant may take magnesium hydroxide (Phillips' Milk of Magnesia; Bayer AG, Leverkusen, Germany) 30 mL by mouth and need to call the urology clinic for further instruction.",[13],"Dietary Supplement: Senna Tab",{"label":15,"type":10,"description":16,"interventionNames":17},"DULCOLAX","Group B participants will be prescribed bisacodyl rectal (Dulcolax Suppository; Sanofi S.A., Paris, France) 1 suppository to be placed rectally on the morning of Post Operative Day (POD)#1. Participant will continue placing a nightly rectal suppository until their first bowel movement. If no bowel movement by the morning of POD#5 participant may take magnesium hydroxide (Phillips' Milk of Magnesia; Bayer AG, Leverkusen, Germany) 30 mL by mouth and need to call the clinic for further instruction.",[18],"Dietary Supplement: Dulcolax Suppositories",[20,27],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DIETARY_SUPPLEMENT","Senna Tab","Senna 8.6mg two tablets per day post operative day 1 and and if needed, then continue on the same dose regiment until post operative day 5.",[9],[26],"Senokot",{"type":21,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"Dulcolax Suppositories","Dulcolax 1 suppository to be placed rectally on the evening of post operative day 1 and if needed, then continue using the same dose regiment until the post operative day 5.",[15],[32],"Bisacodyl Suppositories",[34],{"name":35,"affiliation":5,"role":36},"Candace Parker-Autry, MD","PRINCIPAL_INVESTIGATOR",[38,44],{"name":39,"role":40,"phone":41,"phoneExt":42,"email":43},"Christina M Mezes, MD","CONTACT","336-713-4098",null,"cmezes@wakehealth.edu",{"name":45,"role":40,"phone":41,"phoneExt":42,"email":46},"Sachin N Vyas, MS, PhD","svyas@wakehealth.edu",[48],{"facility":5,"status":49,"city":50,"state":51,"zip":52,"country":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"RECRUITING","Winston-Salem","North Carolina","27157","United States",{"type":55,"coordinates":56},"Point",[57,58],-80.24422,36.09986,{"lat":58,"lon":57},[61,62],{"name":39,"role":40,"phone":41,"phoneExt":42,"email":43},{"name":45,"role":40,"phone":63,"phoneExt":42,"email":46},"336.713.4098",{"type":65,"investigatorFullName":42,"investigatorTitle":42,"investigatorAffiliation":42,"oldNameTitle":42,"oldOrganization":42},"SPONSOR","100541894",false,"NCT06335797","Optimization of Postoperative Bowel Habits","Optimization of Postoperative Bowel Habits Following Pelvic Reconstructive Surgery: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Women ages 18 and older scheduled to undergo vaginal pelvic organ prolapse repair\n\nExclusion Criteria:\n\n* Women younger than 18 years old\n* Those unable to provide consent\n* Preexisting chronic laxative use\n* Conditions that could affect bowel function including, inflammatory bowel disease, irritable bowel syndrome, colorectal cancer, rectovaginal fistula; concurrent bowel surgery; intraoperative bowel injury","FEMALE","18 Years",{"count":75,"type":76},88,"ESTIMATED","INTERVENTIONAL",[79],"NA","Project is a trial, in which women undergoing vaginal surgery for pelvic organ prolapse will be randomized 1:1 to a postoperative bowel regimen of either oral senna or rectal bisacodyl suppository.",[82],"Constipation",[84,85,86],"Bowel Habits","Pelvic Surgery","Laxatives","2026-02-25",{"date":89,"type":90},"2026-02-27","ACTUAL",{"date":92,"type":90},"2024-10-16",{"date":94,"type":76},"2027-05",{"name":5,"class":6},1]