[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100511946":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":31,"locations":39,"responsibleParty":54,"collaborators":10,"id":58,"slug":10,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":10,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":10,"maxAge":10,"enrollmentInfo":65,"targetDuration":68,"studyType":69,"phases":10,"briefSummary":70,"conditions":71,"keywords":74,"overallStatus":41,"whyStopped":10,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"University Medical Center Goettingen","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Otoferlin participant group",null,"Individuals with hearing impairment who have a molecular genetic diagnosis involving otoferlin",[13],"Diagnostic Test: Molecular genetic testing and audiometry",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","Molecular genetic testing and audiometry","Genetic testing and audiometry are the interventions of interest",[9],[21,24,27,29],{"name":22,"affiliation":5,"role":23},"Tobias Moser, MD","STUDY_DIRECTOR",{"name":25,"affiliation":5,"role":26},"Bernd Wollnik, MD","PRINCIPAL_INVESTIGATOR",{"name":28,"affiliation":5,"role":26},"Nicola Strenzke, MD",{"name":30,"affiliation":5,"role":26},"Barbara Vona, PhD",[32,36],{"name":30,"role":33,"phone":34,"phoneExt":10,"email":35},"CONTACT","+49-551-38-51337","barbara.vona@med.uni-goettingen.de",{"name":22,"role":33,"phone":37,"phoneExt":10,"email":38},"+49-551-39-63070","tmoser@gwdg.de",[40],{"facility":5,"status":41,"city":42,"state":43,"zip":44,"country":45,"cosmosGeoPoint":10,"geoPoint":10,"contacts":46},"RECRUITING","Goettigen","Lower Saxony","37075","Germany",[47,48,49,50,52,53],{"name":30,"role":33,"phone":34,"phoneExt":10,"email":35},{"name":22,"role":33,"phone":37,"phoneExt":10,"email":38},{"name":22,"role":26,"phone":10,"phoneExt":10,"email":10},{"name":25,"role":51,"phone":10,"phoneExt":10,"email":10},"SUB_INVESTIGATOR",{"name":28,"role":51,"phone":10,"phoneExt":10,"email":10},{"name":30,"role":51,"phone":10,"phoneExt":10,"email":10},{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Tobias Moser","Prof.","100511946",false,"NCT05946057","Otoferlin Patient Registry and Natural History Study","Patient Registry for Individuals With Otoferlin-Associated Hearing Loss","Inclusion Criteria:\n\n* A molecular genetic diagnosis involving biallelic variants in otoferlin (OTOF) and audiometry\n\nExclusion Criteria:\n\n* Patients with evidence of non-OTOF molecular genetic diagnoses","ALL",{"count":66,"type":67},100,"ESTIMATED","25 Years","OBSERVATIONAL","This registry is designed to collect comprehensive information about the molecular genetic diagnoses of individuals with otoferlin-associated hearing impairment and clinical information to support a natural history study.",[72,73],"Otoferlin-related Auditory Synaptopathy","Hearing Impairment",[75,76],"Otoferlin patient registry","Natural history study","2025-05-21",{"date":79,"type":80},"2025-05-28","ACTUAL",{"date":82,"type":80},"2023-02-21",{"date":84,"type":67},"2048-02-21",{"name":56,"class":6},1]