Outcomes in Pediatric and Young Adult B-Cell Malignancies After Commercially Available Immunotherapy

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeUp to 26
SponsorStanford University

About this trial

To use a consistent and standardized platform to retrospectively and prospectively study children and young adults with B cell malignancies receiving Immunotherapy, blinatumomab and/or inotuzumab ozogamicin.

Eligibility criteria

Qualifiers

Experienced refractory or relapsed disease, treated with standard chemotherapy, without immunotherapy treatment.

Previously undergone standard of care immunotherapy with FDA approved therapies, such as Kymriah™ (CTL019, tisagenlecleucel), blinatumomab or

Age: Greater than or equal to 0 year of age and less than or equal to 26 years of age.

Disease Status - B cell precursor acute lymphoblastic leukemia (ALL) or B cell lymphoma

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Questionnaire for patients receiving therapy

Treatment groups

500 Participants
are divided into 2 treatment groups

Locations

22
Arizona
Banner University Medical Center - Tucson85719, Tucson United States
California
City of Hope Comprehensive Cancer Center91010, Duarte United States
Stanford University94305, Palo Alto United States
UCSF (Benioff Children's)94115, San Francisco United States

Sponsors and collaborators

Stanford University

Lead sponsor

The Pediatric Oncology Experimental Therapeutics Investigators' Consortium

Collaborator