[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100579203":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":15,"responsibleParty":30,"collaborators":32,"id":40,"slug":7,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":7,"eligibilityCriteria":45,"healthyVolunteers":41,"sex":46,"minAge":47,"maxAge":7,"enrollmentInfo":48,"targetDuration":7,"studyType":51,"phases":7,"briefSummary":52,"conditions":53,"keywords":55,"overallStatus":18,"whyStopped":7,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":68},{"fullName":5,"class":6},"Regina Elena Cancer Institute","OTHER",null,[9],{"name":10,"role":11,"phone":12,"phoneExt":13,"email":14},"Antonello Vidiri, Medical Doctor","CONTACT","+39 0652665071","+39","antonello.vidiri@ifo.it",[16],{"facility":17,"status":18,"city":19,"state":19,"zip":20,"country":21,"cosmosGeoPoint":22,"geoPoint":27,"contacts":28},"IRCCS National Cancer Institute \"Regina Elena\"","RECRUITING","Rome","00144","Italy",{"type":23,"coordinates":24},"Point",[25,26],12.51133,41.89193,{"lat":26,"lon":25},[29],{"name":10,"role":11,"phone":12,"phoneExt":13,"email":14},{"type":31,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[33,35,37],{"name":34,"class":6},"University of Campania Luigi Vanvitelli",{"name":36,"class":6},"Federico II University",{"name":38,"class":39},"I.R.C.C.S. Fondazione Santa Lucia, Italy","UNKNOWN","100579203",false,"NCT06821243","Patients With Human Papillomavirus-associated Head and Neck Cancer for the Discovery of Predictive Biomarkers to Guide Clinical Intervention","Multidimensional Assessment of Virus-associated Head and Neck Cancer Patients for the Discovery of Predictive Biomarkers to Guide Clinical Intervention","Inclusion Criteria:\n\n* Squamous cell carcinomas of the oropharynx (OPSCC) candidates for surgical\n* Age \\> 18 years\n* ECOG performance status \\\u003C\\_ 2\n* Signature of informed consent (to participate in the study and data processing)\n\nExclusion Criteria:\n\n* Presence of distant metastases at the time of diagnosis\n* Previous head and neck cancer","ALL","18 Years",{"count":49,"type":50},40,"ESTIMATED","OBSERVATIONAL","Prospective pilot study, non-interventional, of a biological\u002Fradiological nature, which involves the collection of tissue samples, and blood from patients suffering from squamous cell carcinoma of the oropharynx OPSCC for detection of HPV-DNA\u002FRNA and immuno-phenotypic analysis of T cells, study of extracellular vesicles, and dosages of cytokines and chemokines involved in the immune response",[54],"Squamous Cell Carcinoma of Oropharynx",[56,57,58],"carcinoma of the oropharynx","squamous cell carcinoma of the oropharynx","head and neck","2026-06-04",{"date":61,"type":62},"2026-06-05","ACTUAL",{"date":64,"type":62},"2024-07-24",{"date":66,"type":50},"2026-07-24",{"name":5,"class":6},1]