[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100599217":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":19,"locations":25,"responsibleParty":43,"collaborators":10,"id":45,"slug":10,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":10,"eligibilityCriteria":50,"healthyVolunteers":51,"sex":52,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":10,"studyType":58,"phases":10,"briefSummary":59,"conditions":60,"keywords":63,"overallStatus":27,"whyStopped":10,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"Papa Giovanni XXIII Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Pectus patients",null,"Patients who are eligible for Nuss procedure (for pectus excavatum correction) are undergoing \"earlier preoperative percutaneous intercostal cryoneurolysis\" in our institution. They are studied through a physical examination also.",[13],"Other: Physical examination of chest skin",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Physical examination of chest skin","soft touch and thermal (cold and warm) examination",[9],[20],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Stefano Mariconti, MD","CONTACT","00390358347","smariconti@asst-pg23.it",[26],{"facility":5,"status":27,"city":28,"state":29,"zip":30,"country":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"RECRUITING","Bergamo","BG","24100","Italy",{"type":33,"coordinates":34},"Point",[35,36],9.66721,45.69601,{"lat":36,"lon":35},[39,41],{"name":40,"role":22,"phone":10,"phoneExt":10,"email":10},"Stefano Mariconti",{"name":21,"role":42,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"type":42,"investigatorFullName":40,"investigatorTitle":44,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Principal Investigator","100599217",false,"NCT07081620","Percutaneous Intercostal Cryoneuromodulation Onset Timing.","How Long Does it Take for Percutaneous Intercostal Cryoneuromodulation to Produce Cryoanalgesia? A Prospective Observational Study.","Inclusion Criteria:\n\n* Patients who are undergoing preoperative percutaneous intercostal cryoneurolysis for pectus excavatum surgery\n\nExclusion Criteria:\n\n* failure to obtain consent",true,"ALL","12 Years","40 Years",{"count":56,"type":57},20,"ESTIMATED","OBSERVATIONAL","Percutaneous Intercostal Cryoneurolysis is a promising technique that addresses acute postoperative pain after Nuss procedure for pectus excavatum. However its onset timing has not yet been determined. A physical examination would assess the variation of chest skin sensitivity to soft touch, cold (water at 4°C), and heat (water at 40°C) through days following the cryoneurolysis procedure.",[61,62],"Cryotherapy Effect","Pectus Excavatum",[64,65],"Cryoneurolysis","Cryoneuromodulation","2025-07-22",{"date":68,"type":69},"2025-07-23","ACTUAL",{"date":71,"type":69},"2025-06-07",{"date":73,"type":57},"2026-11",{"name":5,"class":6},1]