[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100607079":3},{"organization":4,"outcomesModule":7,"designInfo":25,"detailedDescription":28,"studyPopulation":29,"armGroups":24,"interventions":24,"overallOfficials":24,"centralContacts":30,"locations":36,"responsibleParty":54,"collaborators":24,"id":58,"slug":24,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":24,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":24,"enrollmentInfo":66,"targetDuration":24,"studyType":69,"phases":24,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":39,"whyStopped":24,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Eye & ENT Hospital of Fudan University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":17,"otherOutcomes":24},[9,13],{"measure":10,"description":11,"timeFrame":12},"Refractive prediction error for sphere","Mean absolute error (MAE, diopters) of model-predicted sphere versus clinical reference","At index examination",{"measure":14,"description":15,"timeFrame":16},"Cohen's kappa with 95% CIs between model","Cohen's kappa with 95% CIs between model outputs and clinician-validated reference for per-parameter","At index examination (single time point)",[18,21],{"measure":19,"description":20,"timeFrame":12},"Cylinder prediction error","Mean absolute error (MAE, diopters) of model-predicted Cylinder",{"measure":22,"description":23,"timeFrame":12},"Axis prediction error","Mean absolute error (MAE, diopters) of model-predicted Axis",null,{"allocation":24,"interventionModel":24,"interventionModelDescription":24,"primaryPurpose":24,"observationalModel":26,"timePerspective":27,"maskingInfo":24},"CASE_ONLY","RETROSPECTIVE","This study compares three large language models accessed in their native configurations, without fine-tuning or external tools. For each examination, the original IOLMaster 700 report image was supplied without manual annotation or pre-processing. A standardized instruction required: (i) structured extraction of AL, ACD, LT, WTW, K1\u002FK2 and axes, ΔK, TK1\u002FTK2 and axes, and ΔTK; (ii) binary toric candidacy and T-code according to institutional ALCON mapping; and (iii) refractive recommendations (sphere, cylinder, implantation axis). Each model generated three independent outputs per case. De-identification and IRB oversight (waiver of consent) were implemented according to institutional policy. The unit of enrollment is participants (n=54), with outcomes analyzed per eye (162 eyes) and per model generation where applicable.","cataract patients who had undergone phacoemulsification and implantation of an AcrySof IQ Toric monofocal intraocular lens",[31],{"name":32,"role":33,"phone":34,"phoneExt":24,"email":35},"Xuanqiao Lin","CONTACT","+8615088920668","1532483480@qq.com",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Eye and ENT hospital of Fudan University","RECRUITING","Shanghai","Shanghai Municipality","200000","China","CN",{"type":46,"coordinates":47},"Point",[48,49],121.45806,31.22222,{"lat":49,"lon":48},[52],{"name":32,"role":33,"phone":53,"phoneExt":24,"email":35},"15088920668",{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"SPONSOR_INVESTIGATOR","Jin Yang","Chief Physician","100607079",false,"NCT07183891","Performance of Large Language Models for Structured Recognition and Refractive Prediction","Head-to-Head Evaluation of ChatGPT 4o, GPT-5, and DeepSeek for Structured Extraction, Toric IOL Recommendation, and Refractive Prediction","Inclusion Criteria:\n\n-postoperative corrected distance visual acuity (CDVA) of 0.10 logMAR or better -an absolute IOL rotational stability of less than 10∘ at the 1-month follow-up examination\n\nExclusion Criteria:\n\n* incomplete biometric data on the examination report;\n* a history of previous ocular surgery or ocular trauma\n* the occurrence of intraoperative complications, such as an anterior capsular tear or posterior capsular rupture\n* the development of significant postoperative complications, including but not limited to severe intraocular infection or inadequate pupillary dilation.","ALL","18 Years",{"count":67,"type":68},100,"ESTIMATED","OBSERVATIONAL","We conducted a single-center, retrospective observational study to evaluate large language models (ChatGPT 4o, GPT-5, DeepSeek) for automated interpretation of de-identified IOLMaster 700 reports provided as raster images. Models produced structured biometric extraction, toric IOL recommendation, and refractive predictions (sphere, cylinder, axis). Primary outcomes included parameter-level agreement and refractive error metrics; secondary outcomes included decision-support performance for toric IOL selection and agreement on ordered T-codes. No clinical intervention was performed.",[72],"Cataract",[74,75,76],"cataract","toric IOL","astigmatism","2025-09-14",{"date":79,"type":80},"2025-09-19","ACTUAL",{"date":82,"type":80},"2025-08-01",{"date":84,"type":68},"2035-12-31",{"name":56,"class":6},1]