[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100427857":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":13,"locations":19,"responsibleParty":76,"collaborators":78,"id":81,"slug":7,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":86,"eligibilityCriteria":87,"healthyVolunteers":82,"sex":88,"minAge":89,"maxAge":7,"enrollmentInfo":90,"targetDuration":7,"studyType":93,"phases":7,"briefSummary":94,"conditions":95,"keywords":7,"overallStatus":22,"whyStopped":7,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"Queen Mary University of London","OTHER",null,[9],{"name":10,"affiliation":11,"role":12},"Nikolaos Donos, Prof.","Professor of Periodontology and Implantology","PRINCIPAL_INVESTIGATOR",[14],{"name":15,"role":16,"phone":17,"phoneExt":7,"email":18},"Vandana Luthra, Dr.","CONTACT","02078826348","BHNT.Clinicaloralresearchcentre@nhs.net",[20,44,58,66],{"facility":21,"status":22,"city":23,"state":7,"zip":24,"country":25,"cosmosGeoPoint":26,"geoPoint":31,"contacts":32},"Barts Health NHS Trust Dental Hospital","RECRUITING","London","E1 1BB","United Kingdom",{"type":27,"coordinates":28},"Point",[29,30],-0.12574,51.50853,{"lat":30,"lon":29},[33,36,39,41],{"name":34,"role":16,"phone":35,"phoneExt":7,"email":18},"Nikolaos Donos, DDS, MS, FHEA, PhD","+44(0)2078823063",{"name":37,"role":16,"phone":38,"phoneExt":7,"email":18},"Rinat Ezra Rinat, PhD","+44(0)207 882 6348",{"name":40,"role":12,"phone":7,"phoneExt":7,"email":7},"Nikolaos Donos, DDS PhD",{"name":42,"role":43,"phone":7,"phoneExt":7,"email":7},"Nikolaos D Gkranias, DDS, PhD","SUB_INVESTIGATOR",{"facility":45,"status":22,"city":23,"state":7,"zip":46,"country":25,"cosmosGeoPoint":47,"geoPoint":49,"contacts":50},"Centre for Oral Clinical Research (COCR)","E1 2AD",{"type":27,"coordinates":48},[29,30],{"lat":30,"lon":29},[51,55],{"name":52,"role":16,"phone":53,"phoneExt":7,"email":54},"Rinat Erza, PhD","0207 882 6348","r.ezra@qmul.ac.uk",{"name":56,"role":16,"phone":7,"phoneExt":7,"email":57},"Nikolaos Gkranias, DDS, PhD","n.gkranias@qmul.ac.uk",{"facility":59,"status":22,"city":23,"state":7,"zip":7,"country":25,"cosmosGeoPoint":60,"geoPoint":62,"contacts":63},"St Bartholomew's Hospital, Barts Health NHS Trust",{"type":27,"coordinates":61},[29,30],{"lat":30,"lon":29},[64],{"name":65,"role":16,"phone":7,"phoneExt":7,"email":7},"Anjali Zalin, Dr",{"facility":67,"status":22,"city":68,"state":7,"zip":7,"country":25,"cosmosGeoPoint":69,"geoPoint":73,"contacts":74},"Luton and Dunstable University Hospital","Luton",{"type":27,"coordinates":70},[71,72],-0.41748,51.87967,{"lat":72,"lon":71},[75],{"name":65,"role":16,"phone":7,"phoneExt":7,"email":7},{"type":77,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[79],{"name":80,"class":6},"University College London Hospitals","100427857",false,"NCT04851470","Periodontal Assessment of a Bariatric Care Population","Periodontal Assessment of a Bariatric Care Population, Clinical, Genetic and Microbiological Characteristics. A Cross-sectional Study.","Bariatric","Inclusion Criteria:\n\nEach subject must meet all of the following inclusion criteria to be enrolled in the study:\n\n1. Subject must be over 18 years of age.\n2. Subject must have a BMI of higher or equal to 30 kg\u002F m2\n3. Subject must have voluntarily given written informed consent.\n\nExclusion Criteria:\n\nSubjects meeting any of the following exclusion criteria are not to be enrolled in the study:\n\n1. Subject is currently involved in other research involving the use of antibiotics or novel or unknown medications.\n2. Self-reported pregnancy.\n3. Subject is on chronic treatment (i.e., two weeks or more) with specific medications known to affect periodontal status (phenytoin or cyclosporine) within one month of baseline visit.\n4. Subject knowingly has HIV or Viral Hepatitis.\n5. Patients are completely edentulous.\n6. Subject with uncontrolled systemic illnesses.\n7. Subject is not capable to give informed consent.\n8. Subjects on chronic antibiotic therapy (ie two weeks or more in the previous month).","ALL","18 Years",{"count":91,"type":92},394,"ESTIMATED","OBSERVATIONAL","Our primary aim is to investigate the prevalence and severity of Periodonotal Disease (PD) in a population of obese patients.\n\nOur secondary objectives are to:\n\nInvestigate inflammatory biomarkers that have been associated with PD in the saliva of obese patients.\n\nInvestigate the association of FTO gene (Obesity) polymorphisms with the prevalence of PD in this population.\n\nInvestigate and describe the subgingival microbial flora in obese patients with PD from subgingival dental plaque samples as well as the salivary samples.",[96,97],"Bariatric Surgery Candidate","Obesity","2026-07-01",{"date":100,"type":101},"2026-07-02","ACTUAL",{"date":103,"type":101},"2014-01-31",{"date":105,"type":92},"2027-12-31",{"name":5,"class":6},4]