Perioperative Myocardial Injury in Patients Undergoing Coronary Artery Bypass Grafting: A Prospective Clinical Study

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age21-80
SponsorSecond Hospital of Jilin University

About this trial

Perioperative myocardial injury (PMI) following coronary artery bypass grafting (CABG) is associated with postoperative morbidity, mortality, and long-term outcomes. High-sensitivity troponin assays and cardiac MRI offer reliable diagnostic tools for PMI, but evidence regarding optimal diagnostic thresholds and perioperative imaging strategy is limited. This prospective clinical study aims to determine the incidence of perioperative myocardial injury using multimodal assessments including high-sensitivity troponin, electrocardiogram, echocardiography, cardiac MRI, and perioperative cardiovascular events.

Eligibility criteria

Qualifiers

Age ≥ 21 years

Undergoing CABG for unstable angina

Able to provide written informed consent

No major cardiovascular event in the prior 6 months

Disqualifiers

Significant hepatic, renal, or other major organ dysfunction

Pregnancy or breastfeeding

Withdrawal during the study

Contraindication to cardiac MRI (metal implants, claustrophobia, etc.)

Trial design

Treatments tested in this trial

  • High-Sensitivity Troponin
  • Cardiac MRI

Treatment groups

150 Participants
are divided into 1 treatment group

Locations

1
the Second Hospital of Jilin University130000, ChangchunJilin, China

Sponsors and collaborators

Second Hospital of Jilin University

Lead sponsor