[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100580976":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":29,"locations":39,"responsibleParty":57,"collaborators":24,"id":60,"slug":24,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":61,"sex":67,"minAge":68,"maxAge":24,"enrollmentInfo":69,"targetDuration":24,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":84,"whyStopped":24,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Northwestern University","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"Prosthesis Condition","Participants experience walking with three prosthesis condition and select their most and least preferred.",[12],"Other: Prosthetic foot",{"label":14,"type":15,"description":16,"interventionNames":17},"Physical Therapy","ACTIVE_COMPARATOR","Participants receive either the standard-of-care intervention (control) or an eight-week personalized physical therapy intervention.",[18],"Other: Physical therapy",[20,25],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"Prosthetic foot","The most- and least-preferred prosthetic foot",[9],null,{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"Physical therapy","Personalized physical therapy",[14],[30,35],{"name":31,"role":32,"phone":33,"phoneExt":24,"email":34},"Matthew J Major, PhD","CONTACT","312-503-5731","matthew-major@northwestern.edu",{"name":36,"role":32,"phone":37,"phoneExt":24,"email":38},"Rebecca L Stine, MS","312-503-5726","rstine@northwestern.edu",[40],{"facility":41,"status":24,"city":42,"state":43,"zip":44,"country":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Northwestern University Prosthetics-Orthotics Center","Chicago","Illinois","60611","United States",{"type":47,"coordinates":48},"Point",[49,50],-87.65005,41.85003,{"lat":50,"lon":49},[53,54,55],{"name":31,"role":32,"phone":33,"phoneExt":24,"email":34},{"name":36,"role":32,"phone":37,"phoneExt":24,"email":38},{"name":31,"role":56,"phone":24,"phoneExt":24,"email":24},"PRINCIPAL_INVESTIGATOR",{"type":56,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Matthew Major","Associate Professor","100580976",false,"NCT06844305","Personalized Prosthetic Foot Prescription and Rehabilitation for Veterans With Lower Limb Loss","A Personalized, Patient-Centered Prosthetic Foot Prescription and Rehabilitation Strategy to Maximize Mobility and Satisfaction in Veterans With Lower Limb Loss","OPORP","Inclusion Criteria:\n\n* Unilateral transtibial amputation;\n* At least 6 months post-amputation;\n* A comfortable-fitting prosthetic socket that can be used with endoskeletal components;\n* Sufficient walking abilities to safely complete study activities.\n\nExclusion Criteria:\n\n* Major contralateral limb amputation LLL on the contralateral limb;\n* Currently receiving physical therapy related to gait training or prosthesis use.","ALL","18 Years",{"count":70,"type":71},50,"ESTIMATED","INTERVENTIONAL",[74],"NA","The goal of clinical trial is to assess an integrated, patient-centered strategy combining user preference-based prosthetic foot prescription and subsequent targeted physical therapy to maximize satisfaction and mobility outcomes for Veterans and others with lower limb loss. The main aims it will address are:\n\n* Assess the effect of prosthetic foot selection based on experiential preference as determined using a variable stiffness foot on mobility and satisfaction\n* Assess the effect of a targeted physical therapy intervention following preference-based foot selection on mobility, balance, and satisfaction? Participants will walk with an emulator prosthetic foot to experience three different conditions that emulate different commercial feet to determine their most- and least-preferred foot. Participants' satisfaction, perceived mobility, and functional mobility will be measured and compared between their most- and least-preferred feet using the corresponding commercial feet. Participants will then be randomly assigned to receive either the standard-of-care (control group) or personalized physical therapy intervention for eight weeks using that preferred prosthetic foot. Participants' satisfaction, mobility, and balance will be measured pre- and post-intervention.",[77],"Amputation of Lower Limb",[79,80,81,82,83],"amputation","prosthesis","prescription","physical therapy","personalized","NOT_YET_RECRUITING","2026-06-09",{"date":87,"type":88},"2026-06-10","ACTUAL",{"date":90,"type":71},"2026-12",{"date":92,"type":71},"2029-05",{"name":5,"class":6},1]