A Phase I/II Clinical Study of LBL-024 in Patients With Advanced Malignant Tumors

Trial statusRecruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age18-80
SponsorNanjing Leads Biolabs Co.,Ltd

About this trial

To evaluate the phase I/II clinical study of LBL-024 in the treatment of patients with advanced malignant tumors

Eligibility criteria

Qualifiers

Agree to comply with the trial treatment plan and visit plan, voluntarily agree to sign the informed consent form;

18-75 years old (including boundary value), no gender limit in the I/IIa trial phase;18-80 years old (including boundary value), no gender limit in the IIb trial phase;

The expected survival time is at least 12 weeks

ECOG score is 0-1

Disqualifiers

Receiving other unmarketed clinical research drugs or treatments within 4 weeks before using the research drug for the first time;

Brain parenchymal metastases or meningeal metastases with clinical symptoms, which are not suitable for inclusion in the group by the investigator's judgment;

medical history of immunodeficiency including positive HIV antibody test;

Women who are pregnant or breastfeeding;

Trial design

Treatments tested in this trial

  • LBL-024 for Injection

Treatment groups

396 Participants
are divided into 1 treatment group

Locations

49
Anhui Provincial Hospital230002, HefeiAnhui, China
The First Affiliated Hospital of Anhui Medical University230000, HefeiAnhui, China
The Second Hospital of Anhui Medical University230601, HefeiAnhui, China
Beijing Cancer Hospital100142, BeijingBeijing Municipality, China

Sponsors and collaborators

Nanjing Leads Biolabs Co.,Ltd

Lead sponsor