About this trial

The goal of this clinical trial is to learn if fecal microbiota transplantation can treat in Gastrointestinal cancer patients with chemotherapy / targeted gastrointestinal symptoms. The main question it aims to answer is: To evaluate the effect of fecal microbiota transplantation (FMT) on gastrointestinal tract in patients with gastrointestinal tumors.

Eligibility criteria

Qualifiers

Age ≥ 18 years, gender not restricted;

Estimated survival time ≥ 3 months;

Confirmed diagnosis of gastrointestinal tumors by pathological examination, including esophageal cancer, gastric cancer, colon cancer, rectal cancer, etc.;

TNM staging of cancer in patients is Stage IV;

Disqualifiers

Patients with major organ dysfunction or even failure, including but not limited to cardiac insufficiency or heart failure, renal insufficiency or renal failure, and hepatic insufficiency/hepatic failure;

Uncontrolled or severe infections;

Known history of psychotropic substance abuse, alcoholism, and drug abuse;

Patients with severe infections complicated with septicemia or sepsis;

Trial design

Treatments tested in this trial

  • Fecal microbiota transplantation (FMT)

Treatment groups

90 Participants
are divided into 2 treatment groups

Locations

1
The Second Affiliated Hospital Zhejiang University School of Medicine310009, ZhejiangHangzhou, China

Sponsors and collaborators

Second Affiliated Hospital, School of Medicine, Zhejiang University

Lead sponsor