About this trial

The purpose of this study is to find out whether CRD3874-SI is a safe treatment for participants with acute myeloid leukemia (AML).

Eligibility criteria

Qualifiers

Documentation of Disease

Participant must be ≥ 18 years of age at the time of signing the informed consent form (ICF).

Participant must weigh at least 40 kg

Participant has an Eastern Cooperative Oncology Group (ECOG) performance status score 0-2 (See Appendix I for performance status criteria)

Disqualifiers

Participants with acute promyelocytic leukemia

Participants with isolated myeloid sarcoma

Blast phase of chronic myeloid leukemia

Known active central nervous system leukemia

Trial design

Treatments tested in this trial

  • CRD3874-SI

Treatment groups

24 Participants
are divided into 3 treatment groups

Locations

7
Memorial Sloan Kettering at Basking Ridge (All Protocol Activities)07920, Basking RidgeNew Jersey, United States
Memorial Sloan Kettering Monmouth (All protocol activities)07748, MiddletownNew Jersey, United States
Memorial Sloan Kettering Bergen (All Protocol Activities)07645, MontvaleNew Jersey, United States
Memorial Sloan Kettering Suffolk-Commack (All Protocol Activities)11725, CommackNew York, United States

Sponsors and collaborators

Memorial Sloan Kettering Cancer Center

Lead sponsor