Compare Morphine and Dexmedetomidine as Adjuvants to Bupivacaine in Ultrasound-guided ACB for Postoperative Analgesia After Knee Surgeries

ConditionsPostoperative Analgesia Morphine and Dexmedetomidine

Trial statusNot yet recruiting

Trial phasePhase 1, Phase 2

Trial typeInterventional

Biological sexAll

AgeNot listed

SponsorKafrelsheikh University

About this trial

This study aims to compare morphine and dexmedetomidine as adjuvants to bupivacaine in ultrasound-guided ACB for postoperative analgesia after knee surgeries

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Both sexes.

American Society of Anesthesiologists (ASA) physical status I-II.

Body mass index (BMI) of 20-35 kg/m2.

Undergoing knee surgeries under spinal anesthesia.

Disqualifiers

Any known allergy or contraindication to local anesthetic.

History of substance abuse.

Decompansated cardiac, pulmonary, hepatic, renal disease.

Obese patients with BMI>35kg/m2.

Trial design

Design model

Parallel

Treatments tested in this trial

Adductor Canal Block (ACB) Only
Drug
This study aims to compare morphine and dexmedetomidine as adjuvants to bupivacaine in ultrasound-guided ACB for postoperative analgesia after knee surgeries. Primary outcome: • Time to first rescue analgesia . Secondary outcomes: * Total opioid consumption in 24 hours postoperatively. * Degree of pain using visual analogue scale (VAS). * Degree of patient satisfaction. * Incidence of complication A) Related to block Nerve Injury Vascular Puncture Hematoma B) Related to drug Local Anesthetic Systemic Toxicity (LAST)

Treatment groups

15 Participants

are divided into 3 treatment groups

Group A: Group DExperimental treatment 1 intervention

Group B: Group MExperimental treatment 1 intervention

Group C: Group CExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

Primary outcome:

• Time to first rescue analgesia .

Time frame

24 hours postoperatively.

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Kafrelsheikh University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: