[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100609538":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":40,"locations":46,"responsibleParty":65,"collaborators":67,"id":72,"slug":26,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":75,"acronym":26,"eligibilityCriteria":76,"healthyVolunteers":77,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":26,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":90,"overallStatus":49,"whyStopped":26,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"University of California, San Francisco","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Single dose of aripiprazole","ACTIVE_COMPARATOR","Single dose of aripiprazole, 10mg administered orally. Participant and administrator will be blinded.",[13],"Drug: Aripiprazole 10 MG",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo dose","PLACEBO_COMPARATOR","A single placebo dose will be administered.",[19],"Drug: Placebo",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Aripiprazole 10 MG","The effects of aripiprazole on stuttering and various behavioral and neural outcomes will be studied compared to placebo.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Placebo","Placebo will be compared against aripiprazole for effect on stuttering and various behavioral and neural markers.",[15],[32,35,37],{"name":33,"affiliation":5,"role":34},"John Houde, PhD","PRINCIPAL_INVESTIGATOR",{"name":36,"affiliation":5,"role":34},"Srikantan Nagarajan, PhD",{"name":38,"affiliation":39,"role":34},"Ludo Max, PhD","University of Washington",[41],{"name":42,"role":43,"phone":44,"phoneExt":26,"email":45},"Natalie Brunwin, MS","CONTACT","4154766888","snl-bil@ucsf.edu",[47],{"facility":48,"status":49,"city":50,"state":51,"zip":52,"country":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Biomagentic Imaging Lab","RECRUITING","San Francisco","California","94143","United States",{"type":55,"coordinates":56},"Point",[57,58],-122.41942,37.77493,{"lat":58,"lon":57},[61,63,64],{"name":42,"role":43,"phone":62,"phoneExt":26,"email":45},"415-476-6888",{"name":33,"role":34,"phone":26,"phoneExt":26,"email":26},{"name":36,"role":34,"phone":26,"phoneExt":26,"email":26},{"type":66,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[68,71],{"name":69,"class":70},"National Institute on Deafness and Other Communication Disorders (NIDCD)","NIH",{"name":39,"class":6},"100609538",false,"NCT07215884","Dopamine and Sensorimotor Function in Stuttering","Inclusion Criteria:\n\n* native speakers of American English\n* for adults who stutter, presence of stuttering will be confirmed, with onset before age 6 years\n* Normal hearing\n* Ages of 18 to 65 years\n* healthy adults without hearing-language difficulties\n\nExclusion Criteria:\n\n* self-reported speech-language-hearing difficulties other than stuttering\n* self-reported neurological or psychological problems\n* other medications (drugs that affect dopaminergic system and\u002For benzodiazepines)",true,"ALL","18 Years","65 Years",{"count":82,"type":83},40,"ESTIMATED","INTERVENTIONAL",[86],"PHASE1","This study is being done to understand the effect of aripiprazole on adults who stutter. Stuttering is a disorder that affects speech fluency. This study aims to understand sensorimotor pathways of stuttering and possible interventions.",[89],"Stuttering, Adult",[91,92,93,94,95],"Stuttering","Aripiprazole","Adults with Stuttering","Speech Fluency","Auditory Feedback","2025-10-08",{"date":98,"type":99},"2025-10-14","ACTUAL",{"date":101,"type":99},"2025-09-30",{"date":103,"type":83},"2026-06-30",{"name":5,"class":6},1]