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at 110% of resting motor threshold intensity, delivering a total of 2400 pulses.",[31],{"type":48,"name":73,"description":74,"armGroupLabels":75,"otherNames":11},"Trans-spinal magnetic stimulation (90% MT + 25 Hz)","High frequency stimulation (25 Hz) at 90% of resting motor threshold intensity, delivering a total of 2400 pulses.",[35],{"type":48,"name":77,"description":78,"armGroupLabels":79,"otherNames":11},"Trans-spinal magnetic stimulation (100% MT + 25 Hz)","High frequency stimulation (25 Hz) at 100% of resting motor threshold intensity, delivering a total of 2400 pulses.",[39],{"type":48,"name":81,"description":82,"armGroupLabels":83,"otherNames":11},"Trans-spinal magnetic stimulation (110% MT + 25 Hz)","High frequency stimulation (25 Hz) at 110% of resting motor threshold intensity, delivering a total of 2400 pulses.",[43],[85],{"name":86,"role":87,"phone":88,"phoneExt":11,"email":89},"Kátia Monte-Silva","CONTACT","+55 81 21267579","lana.ufpe@gmail.com",[91],{"facility":5,"status":92,"city":93,"state":94,"zip":95,"country":96,"cosmosGeoPoint":97,"geoPoint":102,"contacts":103},"RECRUITING","Recife","Pernambuco","50740-560","Brazil",{"type":98,"coordinates":99},"Point",[100,101],-34.88111,-8.05389,{"lat":101,"lon":100},[104],{"name":105,"role":87,"phone":106,"phoneExt":11,"email":107},"João Fabrício","+55 81 986450112","joaovmelo2015@gmail.com",{"type":109,"investigatorFullName":86,"investigatorTitle":110,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Professor","100595000",false,"NCT07026760","Effects of Trans-spinal Magnetic Stimulation on Cortical Excitability in Healthy Individuals","Healthy adults aged 18-40 years, of both sexes; right-handed (confirmed via the Edinburgh Handedness Inventory); and for women, consistent use of contraceptive medication to mitigate hormonal influences on nervous system excitability.\n\nExclusion Criteria:\n\nPregnancy; history of seizures or epilepsy; metallic implants in the head, spine, face, or heart; diagnosed neurological or musculoskeletal conditions that could interfere with assessments or interventions; or use of substances that alter nervous system excitability.",true,"ALL","18 Years","40 Years",{"count":121,"type":122},18,"ESTIMATED","INTERVENTIONAL",[125],"PHASE1","This study investigates the immediate effects of different parameters (frequency and intensity) of trans-spinal magnetic stimulation (TsMS) on cortical excitability in healthy individuals. Using a randomized, double-blind crossover design, the research aims to identify optimal stimulation protocols for modulating neural activity. Outcomes include measurements of motor-evoked potentials (MEP), intracortical inhibition (ICI), and facilitation (ICF). Findings may enhance non-invasive therapeutic strategies for neurological disorders.",[128],"Healthy Individuals",[130,131],"Trans-spinal magnetic stimulation","Cortical Excitability","2025-06-10",{"date":134,"type":135},"2025-06-18","ACTUAL",{"date":137,"type":135},"2022-10-01",{"date":139,"type":122},"2025-10-30",{"name":5,"class":6},1]