[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100616592":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":34,"locations":39,"responsibleParty":51,"collaborators":54,"id":58,"slug":25,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":59,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":25,"studyType":71,"phases":72,"briefSummary":75,"conditions":76,"keywords":80,"overallStatus":82,"whyStopped":25,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"University of Alabama at Birmingham","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"High-energy Group","ACTIVE_COMPARATOR","The intervention group receives a standard fortified human milk (maternal or donor) diet plus the DHA\u002FARA supplement for the first 14 days. Infants in this group will be secondarily assigned to either a low-dose (60\u002F120 mg\u002Fkg\u002Fday) or high-dose (120\u002F240 mg\u002Fkg\u002Fday) DHA\u002FARA supplement.",[13],"Dietary Supplement: High-energy group",{"label":15,"type":6,"description":16,"interventionNames":17},"Standard-energy Group","The control group receives a standard fortified human milk (maternal or donor) diet for the first 14 days.",[18],"Other: Standard-energy group",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DIETARY_SUPPLEMENT","High-energy group","Study participants assigned to the intervention group will receive a standard, fortified human milk diet plus a DHA\u002FARA supplement during the first 2 weeks after birth.",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Standard-energy group","Study participants assigned to the intervention group will receive a standard, fortified human milk diet during the first 2 weeks after birth.",[15],[31],{"name":32,"affiliation":5,"role":33},"Ariel A. Salas, MD, MSPH","PRINCIPAL_INVESTIGATOR",[35],{"name":32,"role":36,"phone":37,"phoneExt":25,"email":38},"CONTACT","205-934-4680","asalas@uabmc.edu",[40],{"facility":5,"status":25,"city":41,"state":42,"zip":43,"country":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":25},"Birmingham","Alabama","35233","United States",{"type":46,"coordinates":47},"Point",[48,49],-86.80249,33.52066,{"lat":49,"lon":48},{"type":33,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Ariel A. Salas","Associate Professor",[55],{"name":56,"class":57},"National Heart, Lung, and Blood Institute (NHLBI)","NIH","100616592",false,"NCT07307612","High-energy Human Milk Diets in the First Two Weeks After Birth to Reduce BPD in Extremely Preterm Infants","Improving Lung Health in Premature Babies Through Early Nutrition: The More & Early Nutritional Delivery for Bronchopulmonary Dysplasia (MEND-BPD) Trial","MEND-BPD","Inclusion Criteria:\n\n* Gestational age ≤ 28 weeks of gestation\n* Postnatal age \\\u003C 72 hours\n\nExclusion Criteria:\n\n* Congenital malformations\n* Chromosomal anomalies\n* Terminal illness needing to limit or withhold support","ALL","1 Day","3 Days",{"count":69,"type":70},150,"ESTIMATED","INTERVENTIONAL",[73,74],"PHASE1","PHASE2","This Phase II, parallel-group, masked, randomized clinical trial aims to evaluate whether a DHA\u002FARA-enriched, fortified human milk diet administered during the first 14 days of life reduces respiratory morbidity and improves lung function in extremely preterm (EPT) infants (born at ≤28 weeks gestation).",[77,78,79],"Extreme Prematurity","Enteral Nutrition","Bronchopulmonary Dysplasia",[81],"Prematurity; Extreme","NOT_YET_RECRUITING","2026-06-11",{"date":85,"type":86},"2026-06-12","ACTUAL",{"date":88,"type":70},"2026-08-15",{"date":90,"type":70},"2029-07-31",{"name":5,"class":6},1]