[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633693":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":42,"centralContacts":46,"locations":52,"responsibleParty":67,"collaborators":32,"id":69,"slug":32,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":32,"eligibilityCriteria":74,"healthyVolunteers":70,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":32,"studyType":81,"phases":82,"briefSummary":85,"conditions":86,"keywords":32,"overallStatus":54,"whyStopped":32,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"The First Affiliated Hospital of Xinxiang Medical College","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Combination Therapy Group","EXPERIMENTAL","Bovine type I collagen sponge + human umbilical cord mesenchymal stem cells (HUMSCs)",[13],"Combination Product: HUMSCs combined with bovine type I collagen",{"label":15,"type":16,"description":17,"interventionNames":18},"Collagen Control Group","ACTIVE_COMPARATOR","Bovine type I collagen sponge alone",[19],"Biological: bovine type I collagen",{"label":21,"type":22,"description":23,"interventionNames":24},"Placebo Group","SHAM_COMPARATOR","Sterile blank dressing \u002F Vaseline gauze",[25],"Device: Sterile blank dressing \u002F Vaseline gauze",[27,33,38],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"COMBINATION_PRODUCT","HUMSCs combined with bovine type I collagen","To evaluate the safety and tolerability of human umbilical cord mesenchymal stem cells combined with bovine type I collagen in the treatment of third-degree burn wounds",[9],null,{"type":34,"name":35,"description":36,"armGroupLabels":37,"otherNames":32},"BIOLOGICAL","bovine type I collagen","To evaluate the safety and tolerability of bovine type I collagen in the treatment of third-degree burn wounds",[15],{"type":39,"name":23,"description":40,"armGroupLabels":41,"otherNames":32},"DEVICE","To evaluate the safety and tolerability of sterile blank dressing \u002F vaseline gauze in the treatment of third-degree burn wounds.",[21],[43],{"name":44,"affiliation":5,"role":45},"Wenjie Ren","PRINCIPAL_INVESTIGATOR",[47,51],{"name":44,"role":48,"phone":49,"phoneExt":32,"email":50},"CONTACT","13937354075","13937354075@163.com",{"name":44,"role":48,"phone":32,"phoneExt":32,"email":32},[53],{"facility":5,"status":54,"city":55,"state":56,"zip":32,"country":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"RECRUITING","Xinxiang","Henan","China",{"type":59,"coordinates":60},"Point",[61,62],113.80151,35.19033,{"lat":62,"lon":61},[65,66],{"name":44,"role":48,"phone":49,"phoneExt":32,"email":50},{"name":44,"role":48,"phone":32,"phoneExt":32,"email":32},{"type":68,"investigatorFullName":32,"investigatorTitle":32,"investigatorAffiliation":32,"oldNameTitle":32,"oldOrganization":32},"SPONSOR","100633693",false,"NCT07530003","HUMSCs Combined With Col I to Third-Degree Burn Wound","A Single-Center, Randomized, Double-Blind, Placebo-Controlled Exploratory Clinical Study of Human Umbilical Cord Mesenchymal Stem Cells Combined With Bovine Type I Collagen for Promoting Third-Degree Burn Wound Repair","Inclusion Criteria:\n\n* Aged 18-65 years, gender unrestricted\n* Confirmed third-degree burns, wound area 1%-5% TBSA\n* Admission within 72 hours after burn injury\n* Voluntarily signed informed consent\n* Able to cooperate and complete follow-up\n\nExclusion Criteria:\n\n* Pregnant or lactating females\n* Severe immunodeficiency or autoimmune disease\n* History of malignant tumor, or coagulation dysfunction\n* Severe cardiac, hepatic, or renal insufficiency\n* Hypersensitivity to collagen or stem cell components\n* Uncontrollable severe wound infection\n* Participation in other clinical studies within the past 3 months\n* Inability to comply with follow-up","ALL","18 Years","65 Years",{"count":79,"type":80},108,"ESTIMATED","INTERVENTIONAL",[83,84],"PHASE1","PHASE2","To evaluate the safety and tolerability of human umbilical cord mesenchymal stem cells combined with bovine type I collagen in the treatment of third-degree burn wounds.",[87,88],"Burn Wounds","Third-Degree Burn Wounds","2026-04-28",{"date":91,"type":92},"2026-05-04","ACTUAL",{"date":94,"type":80},"2026-04-06",{"date":96,"type":80},"2028-12-31",{"name":5,"class":6},1]